News tagged with statins

Related topics: heart disease , drug , heart attack , cholesterol

Statin use decreases the risk of Barrett's esophagus

Statins, a class of drugs commonly used to lower cholesterol levels, significantly reduce a patient's risk of developing Barrett's esophagus, according to a new study in Gastroenterology, the official journal of the Americ ...

3 hours ago
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New research finds statins don't reduce skin cancer risk

(Medical Xpress) -- Murmurings over the past couple of years suggesting that certain statins might reduce the risk for people developing skin cancer, have proven to be unfounded. New research by a team working out of the ...

Apr 23, 2012
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New signal stabilizes atherosclerotic plaques

Atherosclerosis is an inflammatory disease with accumulation of cholesterol in the vessel walls. The atherosclerotic plaque is built up throughout life and when it ruptures it leads to heart attack or stroke. T cells are ...

Jul 31, 2013
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Study finds no link between statins and cancer risk

(Medical Xpress) -- A new study published in the Journal of the American College of Cardiology reports that, contrary to previous studies, the use of cholesterol reducing statin drugs does not increase the risk of patien ...

Jul 25, 2011
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Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

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