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Research reveals possible reason for cholesterol-drug side effects

The U.S. Food and Drug Administration and physicians continue to document that some patients experience fuzzy thinking and memory loss while taking statins, a class of global top-selling cholesterol-lowering ...

Medical research created May 10, 2013 | popularity 4.5 / 5 (11) | comments 13 | with audio podcast

Cholesterol drugs might boost kidney cancer survival

(HealthDay)—Cholesterol-lowering statin drugs that are taken by millions of Americans might also improve survival from a type of kidney cancer called renal cell carcinoma, a new study suggests.

Cancer created May 07, 2013 | popularity 5 / 5 (1) | comments 0

New research finds statins don't reduce skin cancer risk

(Medical Xpress) -- Murmurings over the past couple of years suggesting that certain statins might reduce the risk for people developing skin cancer, have proven to be unfounded. New research by a team working out of the ...

Cancer created Apr 23, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast report

Monthly shot lowers cholesterol 66 percent: study

A monthly injection of an experimental drug made by the US biotech firm Amgen reduced patients' cholesterol by up to 66 percent, according to a small study described at a US cardiology conference.

Cardiology created Mar 26, 2012 | popularity 5 / 5 (2) | comments 5

The cost of prescription drugs—a comparison of two countries

In the United States, the cost paid for statins (drugs to lower cholesterol) in people under the age of 65 who have private insurance continues to exceed comparable costs paid by the government in the United Kingdom (U.K.) ...

Medications created Nov 01, 2012 | popularity 3.7 / 5 (3) | comments 1

Study finds no link between statins and cancer risk

(Medical Xpress) -- A new study published in the Journal of the American College of Cardiology reports that, contrary to previous studies, the use of cholesterol reducing statin drugs does not increase the risk of patien ...

Cancer created Jul 25, 2011 | popularity 5 / 5 (2) | comments 0 | with audio podcast report

Study: Mega vitamins won't help after heart attack, chelation treatment might

(HealthDay)—There's mixed news from a much-anticipated clinical trial for people who've suffered a heart attack: While a study found that daily high doses of vitamins and minerals did nothing to improve ...

Cardiology created Mar 11, 2013 | popularity 1 / 5 (1) | comments 0 | with audio podcast

Statins are unlikely to prevent blood clots, analysis finds

Despite previous studies suggesting the contrary, statins (cholesterol-lowering drugs) may not prevent blood clots (venous thrombo-embolism) in adults, according to a large analysis by international researchers published ...

Cardiology created Sep 18, 2012 | popularity 3 / 5 (2) | comments 1 | with audio podcast

Risk of new-onset diabetes varies with different statins

(HealthDay)—Different types and doses of statins seem to correlate with distinct risks of developing new-onset diabetes mellitus (DM), according to a meta-analysis published in the April 15 issue of The Am ...

Cancer created Apr 11, 2013 | popularity not rated yet | comments 0

Medical studies with striking results often prove false

If a medical study seems too good to be true, it probably is, according to a new analysis.

Cancer created Oct 24, 2012 | popularity 4 / 5 (1) | comments 2

Open-angle glaucoma up 22 percent in last 10 years

(HealthDay)—The prevalence of open-angle glaucoma has increased more than 20 percent in the last 10 years and currently affects more than 2.7 million Americans age 40 years and older, according to a report ...

Ophthalmology created Jan 01, 2013 | popularity 5 / 5 (1) | comments 0

Report: Cancer now leading cause of death in US hispanics

A new report from American Cancer Society researchers finds that despite declining death rates, cancer has surpassed heart disease as the leading cause of death among Hispanics in the U.S. In 2009, the most recent year for ...

Cancer created Sep 17, 2012 | popularity not rated yet | comments 0

Drug protects against kidney injury from imaging dye in ACS patients

High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research ...

Cardiology created Mar 11, 2013 | popularity not rated yet | comments 0

Cholesterol medicine affects energy production in muscles

Up to 75 per cent of patients who take statins to treat elevated cholesterol levels may suffer from muscle pain. Scientists at the Center for Healthy Aging at the University of Copenhagen have now identified ...

Cardiology created Jan 03, 2013 | popularity 5 / 5 (2) | comments 0

Potency of statins linked to muscle side effects

A study from the University of California, San Diego School of Medicine, published August 22 online by PLoS ONE, reports that muscle problems reported by patients taking statins were related to the strength or potency of the ...

Medical research created Aug 22, 2012 | popularity not rated yet | comments 1 | with audio podcast

Statin

The statins (or HMG-CoA reductase inhibitors) are a class of drugs that lower cholesterol levels in people with or at risk of cardiovascular disease.

They lower cholesterol by inhibiting the enzyme HMG-CoA reductase, which is the rate-limiting enzyme of the mevalonate pathway of cholesterol synthesis. Inhibition of this enzyme in the liver results in decreased cholesterol synthesis as well as increased synthesis of LDL receptors, resulting in an increased clearance of low-density lipoprotein (LDL) from the bloodstream. The first results can be seen after one week of use and the effect is maximal after four to six weeks.

For more information about Statin, read the full article at Wikipedia.
This text uses material from Wikipedia and is available under the GNU Free Documentation License.

Related topics: heart disease , drug , heart attack , cholesterol