Oncology & Cancer

How a leukemia hijacks the genes needed by blood stem cells

As a child, Lynn Aureli didn't know that a particular genetic change contributed to her acute myeloid leukemia (AML)—an alteration that eventually would help explain the cancer's lack of response to chemotherapy. Nor was ...

Medications

New drug candidate slows the progression of adrenoleukodystrophy

The work of Professor Fanny Mochel (AP-HP, Sorbonne University) at Paris Brain Institute, in collaboration with clinical research teams in eight countries and Spanish biotech Minoryx Therapeutics, has demonstrated the protective ...

Medical research

Drug can spur liver regeneration in Alagille syndrome

Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...

Oncology & Cancer

Cell therapy could improve bone marrow transplant safety

UCLA researchers report a step forward in the development of an "off-the-shelf" cell therapy that could reduce the severity of graft-versus-host disease in people receiving donor bone marrow transplants for the treatment ...

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