Parkinson's & Movement disorders

How disease mutations affect the Parkin protein

Researchers at the MRC Laboratory of Molecular Biology in the United Kingdom have determined the crystal structure of Parkin, a protein found in cells that when mutated can lead to a hereditary form of Parkinson's disease. ...

Medical research

Discovery reshapes understanding of embryonic development

(Medical Xpress)—When a baby is born, one of the first things a parent will do is count fingers and toes. New research conducted at UC San Francisco sheds lights on how these specialized digits are formed.

Oncology & Cancer

Researchers identify new potential target for cancer therapy

Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase cancer ...

Medical research

Peptides for the treatment of severe diseases

A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively bind disease-related ...

Medical research

When bone-eating cells gain the upper hand

Advanced osteoporosis is often the most severe sequela, or resulting condition, of plasma cell cancer (multiple myeloma). Abnormally functioning stem cells are a key causal factor.

Dentistry

Biological tooth replacement—a step closer

Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells. Current implant-based methods of whole tooth replacement fail to reproduce a natural ...

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