Four stranded DNA structures—known as G-quadruplexes—have been shown to play a role in certain types of breast cancer for the first time, providing a potential new target for personalised medicine, say scientists at the ...
Aug 3, 2020
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Researchers at the University of New Hampshire have identified new pathways in an RNA-based virus where inhibitors, like medical treatments, unbind. The finding could be beneficial in understanding how these inhibitors react ...
Jul 22, 2020
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A large team of researchers affiliated with a very large number of medical institutions across the U.S. and also three from Finland, two from Mexico, and one from the U.K. has mapped structural variants in 17,795 sequenced ...
Like pirates on a treasure hunt, St. Jude Children's Research Hospital scientists have created the first 3-D map of a mouse genome and used it to discover scientific gold. The gold includes insight from machine learning into ...
Sep 4, 2019
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A team of researchers from the U.K., Australia and the U.S. has mapped the structure of the influenza A virus genome. In their paper published in the journal Nature Microbiology, the group describes their genetic analysis ...
Human genomes vary quite a bit from individual to individual. These differences include single nucleotide changes, or "spelling mistakes" in the DNA sequence, but even more variation comes from structural variants, which ...
Apr 16, 2019
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Inside cells DNA is tightly wrapped around proteins and packed in a complex, 3-D structure called chromatin. Chromatin not only protects genetic material from damage, but also organizes the entire genome by regulating the ...
Jan 29, 2019
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Studying the three-dimensional structure of DNA and its dynamics is revealing a lot of information about gene expression, expanding our knowledge of how cells, tissues and organs actually work in health and disease. Properly ...
Oct 31, 2018
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In a pioneering study, scientists at A*STAR's Genome Institute of Singapore (GIS) have developed new machine learning computer models, a type of artificial intelligence (AI), to accurately pinpoint cancer mutations. They ...
Apr 19, 2018
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Last month marked the 10th anniversary of the landmark paper that launched "connectomics", overthrowing the predominant approach to localizing individual functions in the brain in favor of mapping the entirety of the brain's ...
Oct 16, 2015
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