New research by the University at Buffalo Research Institute on Addictions has identified a key mechanism in how aerobic exercise can help impact the brain in ways that may support treatment—and even prevention strategies—for ...
May 28, 2018
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Jessica and Darren McIntosh were too busy to see me when I arrived at their house one Sunday morning. When I returned later, I learned what they'd been busy with: arguing with a family member, also an addict, about a single ...
May 3, 2016
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A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug's "high." The breakthrough ...
Nov 14, 2022
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An Oxford-led team, working with Cambridge and international scholars, has discovered hundreds of genetic markers driving two of life's most momentous milestones—the age at which people first have sex and become parents.
Jul 1, 2021
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If you've ever stayed up late angrily commenting on Twitter posts, eating a whole pint of ice cream out of the container, finishing another bottle of wine, or just feeling miserable, you might identify with the Mind After ...
Aug 2, 2022
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Even though fewer heart attacks are occurring in the U.S.—in large part due to the use of medications like statins and a decline in smoking—these events are steadily rising in very young adults. New data not only validate ...
Mar 7, 2019
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Data from a nationally representative survey indicate that in 2019, nearly three-fourths of U.S. adults reporting buprenorphine use did not misuse the medication in the past 12 months. In addition, buprenorphine misuse among ...
Oct 15, 2021
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Mindfulness might offer more than relief from daily stress. Research now suggests it can boost recovery from addiction and trauma.
Mar 19, 2019
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Research led by the Department of Anthropology and School of Biomedical Sciences, Kent State University, Ohio, has investigated neuropeptide Y innervation in an area of the brain called the nucleus accumbens of various primate ...
The proportion of opioid overdose deaths involving buprenorphine, a medication used to treat opioid use disorder, did not increase in the months after prescribing flexibilities were put in place during the COVID-19 pandemic, ...
Jan 20, 2023
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Although the term substance can refer to any physical matter, substance abuse has come to refer to the overindulgence in and dependence on a chemical leading to effects that are detrimental to the individual's physical and mental health, or the welfare of others.
The disorder is characterized by a pattern of continued pathological use of a fatty foods, that results in repeated adverse social consequences related to eating, such as failure to meet work, family, or school obligations, interpersonal conflicts, or dating problems. There are on-going debates as to the exact distinctions between substance abuse and substance dependence, but current practice standard distinguishes between the two by defining substance dependence in terms of physiological and behavioral symptoms of substance use, and substance abuse in terms of the social consequences of substance use.
Substance abuse may lead to addiction or substance dependence. Medically, physiologic dependence requires the development of tolerance leading to withdrawal symptoms. Both abuse and dependence are distinct from addiction which involves a compulsion to continue using the substance despite the negative consequences, and may or may not involve chemical dependency. Dependence almost always implies abuse, but abuse frequently occurs without dependence, particularly when an individual first begins to abuse a substance. Dependence involves physiological processes while substance abuse reflects a complex interaction between the individual, the abused substance and society.
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