News tagged with suppressor genes
Elimination of two ribosome subunits activates cell cycle control
Alterations in the formation of ribosomes (the elements of the cell where proteins are made) cause the induction of p53 protein and cell cycle disruption. This process is crucial to understand fundamental biological processes ...
Genetics
May 22, 2012 |
not rated yet |
0
Clusters of cooperating tumor-suppressor genes are found in large regions deleted in common cancers
Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
Cancer
May 07, 2012 |
not rated yet |
0
|
Real-time monitoring of cellular signalling events
(Medical Xpress) -- Phosphorylation is one of the most important and ubiquitous cell regulatory events. EU-funded researchers assessed the dynamic events of intracellular phosphorylation in two model systems with important ...
Cancer
May 02, 2012 |
not rated yet |
0
Outwitting a brainy gene
(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...
Cancer
May 01, 2012 |
5 / 5 (2) |
0
Scientists find gene that inhibits pancreas cancer spread
Scientists have identified a gene that slows the spread of pancreatic cancer tumours, paving the way for targeted treatment of one of the deadliest forms of the disease, said a paper published Sunday.
Cancer
Apr 29, 2012 |
5 / 5 (7) |
0
Therapy exploits 'addiction' of leukemia cells
A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules. The research, published by Cell Press online ...
Cancer
Apr 16, 2012 |
not rated yet |
0
Specific inhibition of autophagy may represent a new concept for treatment of kidney cancer
New research at the University of Cincinnati (UC) suggests that kidney cancer growth depends on autophagy, a complex process that can provide cells with nutrients from intracellular sources. Researchers say in certain circumstances ...
Cancer
Apr 16, 2012 |
5 / 5 (1) |
0
'Obscurins' in breast tissue may help physicians predict and detect breast cancer
A new discovery published online in The FASEB Journal may lead to a new tool to help physicians assess breast cancer risk as well as diagnose the disease. In the report, researchers from Johns Hopkins University and the Un ...
Cancer
Mar 21, 2012 |
not rated yet |
0
Gene clue to how virus causes cancer
Virologists and immunologists at Imperial College London and University of Zurich have identified mutations in Epstein-Barr virus (EBV) that increase the capacity of the virus to cause cancer, in a study published ...
Cancer
Mar 19, 2012 |
5 / 5 (3) |
0
|
BRG1 mutations confer resistance to hormones in lung cancer
Retinoic acid (vitamin A) and steroids are hormones found in our body that protect against oxidative stress, reduce inflammation and are involved in cellular differentiation processes. One of the characteristics of tumours ...
Cancer
Mar 15, 2012 |
not rated yet |
0
Researchers uncover new operations of cancer suppressor
(Medical Xpress) -- Scientists at the University of Dundee studying an important tumour suppressor, which is involved in at least a quarter of all cancers, have uncovered new ways in which it works.
Cancer
Feb 24, 2012 |
5 / 5 (1) |
0
New tumor suppressor gene identified
A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...
Cancer
Feb 13, 2012 |
4.8 / 5 (4) |
0
New research sheds light on gene destruction linked to aggressive prostate cancer
Researchers at Queen's University in Kingston, Canada have identified a possible cause for the loss of a tumour suppressor gene (known as PTEN) that can lead to the development of more aggressive forms of prostate cancer.
Cancer
Jan 26, 2012 |
not rated yet |
0
|
Women with certain type of ovarian cancer and BRCA gene mutation have improved survival at 5 years
Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved 5-year ...
Cancer
Jan 24, 2012 |
not rated yet |
0
Why cholesterol-lowering statins might treat cancer
Cholesterol-lowering statins seem to keep breast cancer at bay in some patients. Now researchers reporting in the January 20th issue of the journal Cell, a Cell Press publication, provide clues about how statins might yield ...
Cancer
Jan 19, 2012 |
not rated yet |
0
