News tagged with suppressor genes

Fish oil may hold key to leukemia cure

A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound -- delta-12-protaglandin J3, or D12-PGJ3 ...

Dec 22, 2011
popularity 5 / 5 (16) | comments 1 | with audio podcast

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...

Apr 15, 2013
popularity 5 / 5 (7) | comments 0 | with audio podcast

Cold viruses point the way to new cancer therapies

Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...

Oct 16, 2012
popularity 5 / 5 (5) | comments 0 | with audio podcast

New tumor suppressor gene identified

A recent study published in Clinical Cancer Research suggests that the protein hVps37A suppresses tumor growth in ovarian cancer. The work, which was funded by the Austrian Science Fund FWF, shows, for th ...

Feb 13, 2012
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Gene clue to how virus causes cancer

Virologists and immunologists at Imperial College London and University of Zurich have identified mutations in Epstein-Barr virus (EBV) that increase the capacity of the virus to cause cancer, in a study published ...

Mar 19, 2012
popularity 5 / 5 (3) | comments 0 | with audio podcast

New epigenetic mechanisms for improved cancer therapy

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. ...

Feb 19, 2013
popularity 5 / 5 (3) | comments 0 | with audio podcast

Small molecule shows promise as anti-cancer therapy

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division ...

Jan 13, 2014
popularity 5 / 5 (3) | comments 0 | with audio podcast

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Outwitting a brainy gene

(Medical Xpress) -- The very first in the series of mutations causing colon cancer occurs in the beta-catenin gene; this gene is abnormally activated in about 90 percent of colorectal cancer patients, and in a much smaller ...

May 01, 2012
popularity 5 / 5 (2) | comments 0