Oncology & Cancer

New model helps identify mutations that drive cancer

Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.

Genetics

Researchers discover new thyroid cancer gene

Cleveland Clinic researchers have discovered a new gene associated with Cowden syndrome, an inherited condition that carries high risks of thyroid, breast, and other cancers, and a subset of non-inherited thyroid cancers, ...

Oncology & Cancer

Hacking the programs of cancer stem cells

All of the cells in a tumor are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor. Such cancer stem cells can migrate to other ...

Oncology & Cancer

Taking aim at rare cancer variants

If you walked into a cancer clinic ten years ago as a newly diagnosed patient, you'd likely get "standard of care" treatment based on the location of the cancer in your body and its stage. Make that same visit today and your ...

Oncology & Cancer

Do prostate cancer cells have an Achilles' heel?

Researchers at the University of Illinois at Chicago describe new ways to selectively kill prostate cancer cells by exploiting the cells' revved-up metabolism. They report their findings in the online journal, eLife.

Oncology & Cancer

A gene that fights cancer, but causes it too

An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development ...

Oncology & Cancer

30-year puzzle in breast cancer solved

In a new study published today in Cell Reports, scientists at the Fred Hutchinson Cancer Research Center demonstrate that mice lacking one copy of a gene called CTCF have abnormal DNA methylation and are markedly predisposed ...

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