Genomic deletions promote cancer by carving up or eliminating tumor-suppressor genes, but now scientists report in the journal Nature that the collateral damage they inflict on neighboring genes exposes cancer cells to vulnerabilities ...
Aug 15, 2012
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Researchers at Mount Sinai School of Medicine, the University of Manchester, and the MD Anderson Cancer Center have found a new role for an oncogenic signaling pathway in embryonic stem cell (ESC) self-renewal and in reprogramming ...
Aug 3, 2012
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The body has a built-in system known as autophagy, or 'self-eating,' that controls how cells live or die. Deregulation of autophagy is linked to the development of human diseases, including neural degeneration and cancer.
Aug 1, 2012
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Scientists at Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan-Kettering Cancer Center have amassed strong experimental evidence implying that commonly occurring large chromosomal deletions that are seen in many cancer ...
May 7, 2012
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Scientists have identified a gene that slows the spread of pancreatic cancer tumours, paving the way for targeted treatment of one of the deadliest forms of the disease, said a paper published Sunday.
Apr 29, 2012
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A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound -- delta-12-protaglandin J3, or D12-PGJ3 -- targeted and ...
Dec 22, 2011
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Women with cancer-causing strains of human papillomavirus (HPV) may be at increased risk for cardiovascular disease (CVD) and stroke even when no conventional risk factors for CVD are present.
Oct 24, 2011
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Cells with too few or too many chromosomes have long been known to be a hallmark of cancer — but the cause of this abnormal number of chromosomes has been little understood. Now, in the August 19th issue of Science, ...
Aug 18, 2011
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Researchers have identified a protein long known to regulate gene expression as a potent suppressor of breast cancer growth. Their study, in the journal Oncogene, is the first to demonstrate how this protein, known as Runx3, ...
Jun 27, 2011
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An international team of researchers, led by scientists at the University of California, San Diego School of Medicine, and the Eastern Hepatobiliary Surgery Hospital in China, say a human gene implicated in the development ...
May 16, 2011
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