Medical research

Purging a virus from organ transplants

Human cytomegalovirus (HCMV) is an extremely common virus, which as other members of the herpes virus family causes life-long infections in humans. Most individuals are exposed to HCMV during childhood, yet symptoms can be ...

Medical research

Photopharmacology: Optical control of insulin secretion

Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have chemically modified an anti-diabetic agent so as to make its action dependent on light. The resulting prototype compound, termed JB253, induces release of ...

Medical research

Two sides of a safety switch

Swiss researchers have discovered a new, surprising link between chloracne and a molecule that protects cells against stress: if Nrf2 gets out of control, disfiguring cysts form on the skin.

Genetics

Aging impacts epigenome in human skeletal muscle

Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches help alter the way our cells act and are impacted by environmental factors including diet, ...

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