In Alzheimer's disease, the degeneration of brain cells is linked to formation of toxic protein aggregates and deposits known as amyloid plaques. Similar processes also play an important role in type 2 diabetes. A research ...
Nov 9, 2022
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Alzheimer's is a disease of aggregation. Neurons in the human brain make a protein called amyloid beta. Such proteins on their own, called monomers of amyloid beta, perform important tasks for neurons. But in the brains of ...
Apr 15, 2019
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A team of researchers in the Netherlands has developed an effective antibacterial ointment based on an optimized human peptide. In their paper published in the journal Science Translational Medicine, the group describes developing ...
Atherosclerosis, a lipid-triggered chronic inflammatory disease of the arteries, is the main cause of strokes and heart attacks. An international team of researchers led by the Technical University of Munich (TUM) and the ...
Feb 12, 2021
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When most people hear the word amyloid, they immediately think of Alzheimer's disease. And indeed, it was in the brains of Alzheimer's patients that these dense protein masses were first identified. But it turns out that ...
Aug 1, 2011
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Northwestern Medicine scientists have successfully tested a nontoxic therapy that suppresses Lupus in blood samples of people with the autoimmune disease.
Nov 11, 2013
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Most bacterial species prefer to live in biofilms, where they are protected from antibiotic treatments and can lead to chronic and recurrent diseases in humans. To address this problem, researchers at Nationwide Children's ...
Dec 5, 2019
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A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.
Mar 25, 2019
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Scientists at Rice University and the University of Miami have figured out how synthetic molecules designed at Rice latch onto the amyloid peptide fibrils thought to be responsible for Alzheimer's disease. Their discovery ...
Jul 23, 2013
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Considering what little progress has been made finding drugs to treat Alzheimer's disease, Maikel Rheinstädter decided to come at the problem from a totally different angle—perhaps the solution lay not with the peptide ...
Sep 11, 2018
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