News tagged with t cells
Related topics: cells , immune cells , immune system , white blood cells , immune response
Engineered antibody demonstrated safety, efficacy in wide range of advanced tumors
(Medical Xpress)—The engineered antibody MPDL3280A, which targets a protein called programmed death-ligand 1 (PD-L1), was safe and effective for several cancers, according to phase I study results presented at the AACR ...
Cancer
Apr 10, 2013 |
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Immunotherapy showed promising antileukemia activity in pediatric patients
Researchers using patients' own immune cells in an immunotherapy approach called "anti-CD19 chimeric antigen receptor (CAR) T-cell therapy," achieved responses in children whose acute lymphocytic leukemia (ALL) had returned ...
Cancer
Apr 07, 2013 |
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Engineered T cells kill tumors but spare normal tissue in an animal model
The need to distinguish between normal cells and tumor cells is a feature that has been long sought for most types of cancer drugs. Tumor antigens, unique proteins on the surface of a tumor, are potential targets for a normal ...
Cancer
Apr 07, 2013 |
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Vaccine adjuvant uses host DNA to boost pathogen recognition
Aluminum salts, or alum, have been injected into billions of people as an adjuvant to make vaccines more effective. No one knows, however, how they boost the immune response. In the March 19, 2013, issue of the Proceedings of ...
Medical research
Apr 05, 2013 |
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Researchers first to use common virus to 'fortify' adult stem cells
Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their ...
Medical research
Apr 01, 2013 |
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Major advance in understanding risky but effective multiple sclerosis treatment
A new study by Multiple Sclerosis researchers at three leading Canadian centres addresses why bone marrow transplantation (BMT) has positive results in patients with particularly aggressive forms of MS. The transplantation ...
Neuroscience
Mar 26, 2013 |
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Hunger-spiking neurons could help control autoimmune diseases
Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers ...
Immunology
Mar 25, 2013 |
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T-cell therapy eradicates an aggressive leukemia in two children
Two children with an aggressive form of childhood leukemia had a complete remission of their disease-showing no evidence of cancer cells in their bodies-after treatment with a novel cell therapy that reprogrammed their immune ...
Cancer
Mar 25, 2013 |
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Research reveals protective properties of influenza vaccines
(Medical Xpress)—Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective ...
Diseases, Conditions, Syndromes
Mar 25, 2013 |
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Research on immune-cell therapy could strengthen promising melanoma treatment
A new study of genetically modified immune cells by scientists from UCLA and the California Institute of Technology could help improve a promising treatment for melanoma, an often fatal form of skin cancer.
Cancer
Mar 22, 2013 |
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Functional characteristics of antitumor T cells change w increasing time after therapeutic transfer
Scientists have characterized how the functionality of genetically engineered T cells administered therapeutically to patients with melanoma changed over time. The data, which are published in Cancer Discovery, a journal of the ...
Cancer
Mar 21, 2013 |
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Insights into the immune system, from the fates of individual T cells
By charting the differing fates of individual T cells, researchers have shown that previously unpredictable aspects of the adaptive immune response can be effectively modeled. The crucial question: What determines ...
Medical research
Mar 20, 2013 |
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Researchers identify a promising target for multiple sclerosis treatments
A team of basic and clinical scientists led by the University of Montreal Hospital Research Centre's (CRCHUM) Dr. Nathalie Arbour has opened the door to significantly improved treatments for the symptoms of Multiple Sclerosis ...
Immunology
Mar 19, 2013 |
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Two-pronged immune cell approach could lead to universal shot against flu
Seasonal epidemics of influenza result in nearly 36,000 deaths annually in the United States, according to the Centers for Disease Control. Current vaccines against the influenza virus elicit an antibody response specific ...
Medical research
Mar 14, 2013 |
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Sizing up bone growth: A surprising cellular mechanism drives skeletal proportions
(Medical Xpress)—Stroll through the Harvard Museum of Natural History and gaze up at the whale skeleton looming overhead. Look down at the furry foxes curled up inside their glass display cases. Don't forget ...
Medical research
Mar 14, 2013 |
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