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T cell

T cells belong to a group of white blood cells known as lymphocytes, and play a central role in cell-mediated immunity. They can be distinguished from other lymphocyte types, such as B cells and natural killer cells by the presence of a special receptor on their cell surface called T cell receptors (TCR). The abbreviation T, in T cell, stands for thymus, since this is the principal organ responsible for the T cell's maturation. Several different subsets of T cells have been discovered, each with a distinct function.

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Stem-cell-based strategy boosts immune system in mice

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...

Immunology created May 16, 2013 | popularity 4.8 / 5 (5) | comments 0 | with audio podcast

Transplant experts challenge assumption, describe pathway that leads to organ rejection

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in ...

Medical research created May 15, 2013 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Newly described type of immune cell and T cells share similar path to maturity, according to new study

(Medical Xpress)—Labs around the world, and a core group at Penn, have been studying recently described populations of immune cells called innate lymphoid cells (ILCs). Some researchers liken them to foot soldiers that ...

Immunology created May 14, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast