News tagged with tangles
Researchers at Washington University School of Medicine in St. Louis have identified a new set of genetic markers for Alzheimer's that point to a second pathway through which the disease develops.
Alzheimer's disease & dementia Apr 04, 2013 | 5 / 5 (2) | 0 |
UCLA researchers have used a brain-imaging tool and stroke risk assessment to identify signs of cognitive decline early on in individuals who don't yet show symptoms of dementia.
Neuroscience Apr 03, 2013 | not rated yet | 0 |
Injecting synthetic tau fibrils into animal models induces Alzheimer's-like tau tangles and imitates the spread of tau pathology, according to research from the Perelman School of Medicine at the University of Pennsylvania ...
Neuroscience Mar 15, 2013 | not rated yet | 0
Brain diseases associated with the misformed protein tau, including Alzheimer's disease and frontotemporal lobar degeneration with tau pathologies, are characterized by neurofibrillary tangles (NFTs) comprised ...
Neuroscience Jan 15, 2013 | 5 / 5 (3) | 0 |
The two infamous proteins, amyloid-beta (Aβ) and tau, that characterize advanced Alzheimer's disease (AD), start healthy neurons on the road to cell death long before the appearance of the deadly plaques and tangles by working ...
Alzheimer's disease & dementia Dec 17, 2012 | 5 / 5 (1) | 0
Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.
Alzheimer's disease & dementia Dec 03, 2012 | 5 / 5 (1) | 0 |
The discovery of the molecular pathway that drives the changes seen in the brains of Alzheimer's patients is reported today, revealing new targets for drug discovery that could be exploited to combat the disease. The study ...
Alzheimer's disease & dementia Nov 20, 2012 | 4.5 / 5 (2) | 0 |
The findings of a new study suggest that the protective effects of an active cognitive lifestyle arise through multiple biological pathways.
Psychology & Psychiatry Apr 25, 2012 | 5 / 5 (4) | 0 |
New research in humans published today reveals that the so-called FKBP52 protein may prevent the Tau protein from turning pathogenic. This may prove significant for the development of new Alzheimer's drugs and for detecting ...
Alzheimer's disease & dementia Mar 20, 2012 | not rated yet | 0
A compound that previously progressed to Phase II clinical trials for cancer treatment slows neurological damage and improves brain function in an animal model of Alzheimer's disease, according to a study ...
Alzheimer's disease & dementia Mar 13, 2012 | not rated yet | 0 |
One of the most distinctive signs of the development of Alzheimer's disease is a change in the behavior of a protein that neuroscientists call tau. In normal brains, tau is present in individual units essential to neuron ...
Neuroscience Feb 02, 2012 | 5 / 5 (4) | 1 |
French scientists said on Tuesday that lack of a key brain protein was linked to Alzheimer's, a finding that threw up a tempting target for drugs to fight the disease.
Neuroscience Jan 24, 2012 | 5 / 5 (1) | 0
The brains of individuals with Alzheimer's disease contain protein aggregates called plaques and tangles, which interfere with normal communication between nerve cells and cause progressive learning and memory ...
Neuroscience Dec 09, 2011 | not rated yet | 0
Depression is one of the most common mental disorders in the elderly, but little is known about the underlying biology of its development in older adults.
Psychology & Psychiatry Nov 08, 2011 | 5 / 5 (1) | 2 |
Neurofibrillary tangles odd, twisted clumps of protein found within nerve cells are a pathological hallmark of Alzheimer's disease. The tangles, which were first identified in the early 1900s by German psychiatrist ...
Medical research Nov 02, 2011 | not rated yet | 0