Peptides for the treatment of severe diseases
A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...
Medical research
Apr 15, 2013 |
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Soy-based compound may reduce tumor cell proliferation in colorectal cancer
Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting. ...
Cancer
Apr 11, 2013 |
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New genetic screen paves the way for long-sought treatments for liver disease
Chronic liver failure is a major health problem that causes about one million deaths around the world each year. A study published April 11th by Cell Press in the journal Cell reveals a new type of screen for identifying genes ...
Medical research
Apr 11, 2013 |
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Fractalkine: New protein target for controlling diabetes
Researchers at the University of California, San Diego School of Medicine have identified a previously unknown biological mechanism involved in the regulation of pancreatic islet beta cells, whose role is to produce and release ...
Diabetes
Apr 11, 2013 |
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Study finds new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Cancer
Apr 11, 2013 |
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U-M researchers find new way to clear cholesterol from the blood
Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.
Cardiology
Apr 10, 2013 |
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Study reveals Rx target for HPV, Hep C and related cancers
New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...
Medical research
Apr 10, 2013 |
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Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...
Cancer
Apr 09, 2013 |
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Improving the search for new schizophrenia treatments
(Medical Xpress)—Controlling the symptoms of schizophrenia is the job of antipsychotic drugs which block a set of specific neural signals. But the way these drugs work can lead to a host of severe and debilitating ...
Psychology & Psychiatry
Apr 05, 2013 |
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Researchers say one specific microrna promotes tumor growth and cancer spread
Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in ...
Cancer
Apr 03, 2013 |
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Third-generation device significantly improves capture of circulating tumor cells
A new system for isolating rare circulating tumor cells (CTCs) – living solid tumor cells found at low levels in the bloodstream – shows significant improvement over previously developed devices and does ...
Cancer
Apr 03, 2013 |
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Breast cancer researchers find new drug target companion prognostic test for hormone therapy resistance
A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive ...
Cancer
Apr 01, 2013 |
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Scientists investigate potential markers for a response to sunitinib in patients with metastatic RCC
Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumours might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a ...
Cancer
Mar 18, 2013 |
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Novel treatment approach for bladder pain using a herpes simplex virus vector reported
Severe chronic pain associated with conditions such as bladder pain syndrome/interstitial cystitis often require the use of opioid medication, with the risk of dependency and serious adverse reactions. An ...
Genetics
Mar 14, 2013 |
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Study reveals therapeutic targets to alter inflammation, type 2 diabetes
New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms. The study, published in the Proceedings of th ...
Inflammatory disorders
Mar 12, 2013 |
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