Cancer stem cells isolated from kidney tumors
Scientists have isolated cancer stem cells that lead to the growth of Wilms' tumours, a type of cancer typically found in the kidneys of young children. The researchers have used these cancer stem cells to test a new therapeutic ...
Cancer
Dec 13, 2012 |
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Scientists identify new biomarker for cancer in bone marrow: Promise for patients of multiple myeloma
Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow. Patients with this form of cancer usually do not ...
Cancer
Dec 13, 2012 |
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Weekly dose reduces targeted drug's side effects, but not its activity against ALL
A potent chemotherapy agent wrapped within a monoclonal antibody selectively destroys the malignant cells responsible for acute lymphocytic leukemia (ALL) in either weekly or monthly dosing, researchers report at the 54th ...
Cancer
Dec 11, 2012 |
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Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...
Cancer
Dec 10, 2012 |
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New research opens new pathway for the treatment of Alzheimer's disease
Scientists from VIB and KU Leuven have discovered a new target molecule for the development of a treatment against Alzheimer's disease. There is currently no cure for this disease. Many candidate drugs fail because they also ...
Alzheimer's disease & dementia
Dec 03, 2012 |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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Scientists uncover a novel cooperative effort to stop cancer spread
(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the ...
Cancer
Nov 28, 2012 |
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Genome packaging: Key to breast cancer development
Cancer is a complex disease and only thanks to advances in genomic techniques have researchers begun to understand, at a cellular and molecular level, the mechanisms which are disrupted in cancer cells. This ...
Cancer
Nov 22, 2012 |
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A more complicated network than generally accepted may control maturation of B cells in the immune system
The process of blood cell development, known as hematopoiesis, gives rise to numerous different immune cell subtypes. Each of these in turn matures through a stepwise process governed by the action of transcription ...
Medical research
Nov 22, 2012 |
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Discovery of nitric oxide delivery mechanism may point to new avenue for treating high blood pressure
(Medical Xpress)—Researchers at the University of Virginia School of Medicine have shed new light on blood pressure regulation with the discovery of an unexpected mechanism by which hemoglobin controls the delivery of nitric ...
Medical research
Nov 14, 2012 |
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Doubling down against diabetes: Turbo-charged gut hormones
A collaboration between scientists in Munich, Germany and Bloomington, USA may have overcome one of the major challenges drug makers have struggled with for years: Delivering powerful nuclear hormones to specific tissues, ...
Medical research
Nov 13, 2012 |
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First trial in humans of 'minicells': A completely new way of delivering anti-cancer drugs
A completely new way of delivering anti-cancer drugs to tumours, using 'minicells' derived from bacteria, has been tested for the first time in humans and found to be safe, well-tolerated and even induced stable disease in ...
Cancer
Nov 08, 2012 |
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Mesothelioma drug slows disease progression in patients with an inactive NF2 gene
Preliminary findings from the first trial of a new drug for patients with mesothelioma show that it has some success in preventing the spread of the deadly disease in patients lacking an active tumour suppressor gene called ...
Cancer
Nov 08, 2012 |
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New targeted therapy for advanced prostate cancer shows anti-tumor activity in clinical trials
Few available treatment options exist once prostate cancer has spread to other parts of the body and has failed to respond to therapies that involve blocking the male hormone androgen. Patients with advanced, hormone-refractory ...
Cancer
Nov 07, 2012 |
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New drug target found for cystic fibrosis lung disease
Vancouver researchers have discovered the cellular pathway that causes lung-damaging inflammation in cystic fibrosis (CF), and that reducing the pathway's activity also decreases inflammation. The finding offers a potential ...
Inflammatory disorders
Nov 07, 2012 |
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