Loss of protective heart failure protein linked to critical limb ischemia
Restoring diminished levels of a protein shown to prevent and reverse heart failure damage could also have therapeutic applications for patients with critical limb ischemia (CLI), suggests a new preclinical study published ...
Medical research
Oct 10, 2012 |
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Study identifies adhesion molecules key to cancer's spread through the body
Although tumor metastasis causes about 90 percent of cancer deaths, the exact mechanism that allows cancer cells to spread from one part of the body to another is not well understood. One key question is ...
Cancer
Oct 09, 2012 |
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Endotrophin links obesity to breast cancer progression
Fat cells (adipocytes) surround breast tumors and contribute to tumor growth by expressing factors that aid oncogenesis. Col6 is a protein that is highly expressed in adipocytes and its expression is further increased in ...
Cancer
Oct 08, 2012 |
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Notch control of cell architecture: Potential implications for future cancer therapy
Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch ...
Cancer
Oct 05, 2012 |
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Researchers show Myc protein is cancer's 'volume control'
(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.
Cancer
Oct 01, 2012 |
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Deafness genetic mutation discovered
Researchers at the University of Cincinnati (UC) and Cincinnati Children's Hospital Medical Center have found a new genetic mutation responsible for deafness and hearing loss associated with Usher syndrome type 1.
Genetics
Sep 30, 2012 |
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Investigational brain cancer vaccine to be tested: Peptide vaccine targets cancer survival protein
(Medical Xpress)—A new clinical research study at Roswell Park Cancer Institute (RPCI) will test a first-of-its-kind cancer "vaccine" that may prove effective against many forms of solid-tumor cancers. The vaccine, to be ...
Cancer
Sep 28, 2012 |
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Aggressive cancer exploits MYC oncogene to amplify global gene activity
Whitehead Institute researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, ...
Cancer
Sep 27, 2012 |
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Researchers find possible key to regulation of ovarian cancer stem cells
(Medical Xpress)—Researchers at Moffitt Cancer Center have discovered that the micro ribonucleic acid miR-214 plays a critical role in regulating ovarian cancer stem cell properties. This knowledge, said the researchers, ...
Cancer
Sep 27, 2012 |
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Study shows steps to isolate stem cells from brain tumors
A new video protocol in Journal of Visualized Experiments (JoVE) details an assay to identify brain tumor initiating stem cells from primary brain tumors. Through flow cytometry, scientists separate stem ...
Medical research
Sep 25, 2012 |
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Mechanism that leads to sporadic Parkinson's disease identified
Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement ...
Parkinson's & Movement disorders
Sep 25, 2012 |
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Therapeutic impact of cell transplantation aided by magnetic factor
Two studies in the current issue of Cell Transplantation (21:6), now freely available on-line, demonstrate how the use of magnetic particles are a factor that can positively impact on the targeted delivery of transplante ...
Medical research
Sep 24, 2012 |
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RNA interference for human therapy
Leading scientists in the field investigated the potential of RNA interference (RNAi) technology as a therapeutic intervention for down-regulating the expression of disease-associated genes. Project deliverables ...
Medical research
Sep 20, 2012 |
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A solution to reducing inflammation
Research carried out at The University of Manchester has found further evidence that a simple solution, which is already used in IV drips, is an effective treatment for reducing inflammation.
Inflammatory disorders
Sep 20, 2012 |
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New molecule with anti-cancer and anti-metastatic properties
A new molecule with anti-cancer and anti-metastatic properties has been discovered by teams from CNRS, CEA, the Institut Curie and Inserm, in collaboration with Australian and British researchers. This anticancer ...
Cancer
Sep 04, 2012 |
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