News tagged with target genes
Related topics: genes , gene expression , cancer cells , cells , transcription factors
Scientists find clues to some inherited heart diseases
(Medical Xpress)—Cornell researchers have uncovered the basic cell biology that helps explain heart defects found in diseases known as laminopathies, a group of some 15 genetic disorders that include forms ...
Medical research
May 07, 2013 |
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Team finds markers related to ovarian cancer survival and recurrence
(Medical Xpress)—Researchers at the University of Illinois have identified biomarkers that can be used to determine ovarian cancer survival and recurrence, and have shown how these biomarkers interact with ...
Cancer
Apr 30, 2013 |
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Hundreds of alterations and potential drug targets to starve cancer tumors identified
A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, ...
Cancer
Apr 21, 2013 |
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Novel monoclonal antibody inhibits tumor growth in breast cancer and angiosarcoma
A monoclonal antibody targeting a protein known as SFPR2 has been shown by researchers at the University of North Carolina to inhibit tumor growth in pre-clinical models of breast cancer and angiosarcoma.
Cancer
Apr 19, 2013 |
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Evolving genes lead to evolving genes
Researchers have designed a method that can universally test for evolutionary adaption, or positive (Darwinian) selection, in any chosen set of genes, using re-sequencing data such as that generated by the 1000 Genomes Project. ...
Genetics
Apr 18, 2013 |
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Study finds new drug target for metastatic breast cancer
Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the ...
Cancer
Apr 11, 2013 |
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Study reveals Rx target for HPV, Hep C and related cancers
New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" ...
Medical research
Apr 10, 2013 |
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Six2 homeoprotein allows breast cancer cells to detach and metastasize
In results presented at the AACR Annual Meeting 2013, researchers from the University of Colorado Cancer Center show that the Six2 homeoprotein, while not involved in primary tumor growth, allows cells to detach from substrate ...
Cancer
Apr 09, 2013 |
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KDM1 may represent a new therapeutic target for glioma
Researchers have generated preclinical data demonstrating that the protein KDM1, which functions as a lysine demethylase, is a potential target for glioma treatment, according to Gangadhara R. Sareddy, Ph.D., a postdoctoral ...
Cancer
Apr 08, 2013 |
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Scientists investigate potential markers for a response to sunitinib in patients with metastatic RCC
Markers such as CA9, CD31, CD34 and VEGFR1/2 in the primary tumours might serve as predictors of a good response to a sunitinib treatment in patients with metastatic clear cell renal cell carcinoma (ccRCC), according to a ...
Cancer
Mar 18, 2013 |
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Novel treatment approach for bladder pain using a herpes simplex virus vector reported
Severe chronic pain associated with conditions such as bladder pain syndrome/interstitial cystitis often require the use of opioid medication, with the risk of dependency and serious adverse reactions. An ...
Genetics
Mar 14, 2013 |
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Combining plasma screening methods better identifies diagnostic and therapeutic targets
For the first time, scientists have combined genomic and proteomic analysis of blood plasma to enhance identification of genetically regulated protein traits. This could be applied to any large association study of civilization ...
Genetics
Feb 08, 2013 |
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A scanner for hereditary defects
Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...
Genetics
Jan 24, 2013 |
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Study provides new drug target for Her-2 related breast cancer
Research led by Dr. Suresh Alahari, the Fred Brazda Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans and its Stanley S. Scott Cancer Center, details exactly how the Her2 cancer gene ...
Cancer
Jan 22, 2013 |
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Discovering a new role for a breast cancer gene
(Medical Xpress)—Researchers at the School of Biosciences have identified an unexpected role for a tumour-associated gene in breast cancer.
Cancer
Jan 18, 2013 |
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