News tagged with target genes
Related topics: genes , gene expression , cancer cells , cells , transcription factors
Mesothelioma drug slows disease progression in patients with an inactive NF2 gene
Preliminary findings from the first trial of a new drug for patients with mesothelioma show that it has some success in preventing the spread of the deadly disease in patients lacking an active tumour suppressor gene called ...
Cancer
Nov 08, 2012 |
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New developments reveal a molecule with a promising function in terms of cancer treatment.
Researchers from Inserm and CNRS from the Institute for genetics and molecular and cellular biology (IGBMC) and from the Research Institute at the Strasbourg school of biotechnology (Irebs) have focussed their efforts on ...
Cancer
Oct 30, 2012 |
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Cold viruses point the way to new cancer therapies
Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...
Cancer
Oct 16, 2012 |
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Finding the origins of infant leukaemia
Leukaemia arises as a result of genetic or epigenetic alterations in blood cells, leading to an aberrant accumulation of undifferentiated blasts. Understanding the molecular pathogenesis and aetiology of ...
Cancer
Oct 15, 2012 |
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Notch control of cell architecture: Potential implications for future cancer therapy
Dissecting the mechanisms implicated in cell architecture should provide new insights for understanding development and tissue morphogenesis in general. An European study focused on the role of the Notch ...
Cancer
Oct 05, 2012 |
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Putting a 'HEX' on muscle regeneration
A complex genetic regulatory network mediates the regeneration of adult skeletal muscles. In this issue of the Journal of Clinical Investigation, researchers at the State University of New York Downstate Medical Center in Bro ...
Medical research
Oct 01, 2012 |
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Researchers show Myc protein is cancer's 'volume control'
(Medical Xpress)—A protein called Myc, commonly found at high levels inside cancer cells, fuels the disease by allowing cells to override their in-built self-destruct mechanisms, according to two new studies by US scientists.
Cancer
Oct 01, 2012 |
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Common RNA pathway found in ALS and dementia
Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, ...
Neuroscience
Sep 30, 2012 |
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Aggressive cancer exploits MYC oncogene to amplify global gene activity
Whitehead Institute researchers have determined the mechanism used by c-Myc to increase the expression of all active genes in cancer cells. Elevated levels of c-Myc are linked to increased rates of metastasis, disease recurrence, ...
Cancer
Sep 27, 2012 |
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Mechanism that leads to sporadic Parkinson's disease identified
Researchers in the Taub Institute at Columbia University Medical Center (CUMC) have identified a mechanism that appears to underlie the common sporadic (non-familial) form of Parkinson's disease, the progressive movement ...
Parkinson's & Movement disorders
Sep 25, 2012 |
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RNA interference for human therapy
Leading scientists in the field investigated the potential of RNA interference (RNAi) technology as a therapeutic intervention for down-regulating the expression of disease-associated genes. Project deliverables ...
Medical research
Sep 20, 2012 |
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ENCODE project: Yale team finds order amidst the chaos within the human genome
The massive Encyclopedia of DNA Elements (ENCODE) unveiled Sept. 5 reveals a human genome vastly more rich and complex than envisioned even a decade ago. In a key supporting paper published in the journal Nature, the lab of ...
Genetics
Sep 05, 2012 |
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Promising new drug target discovered for treatment and prevention of heart failure
A promising new drug target for the treatment and prevention of heart failure has been discovered by researchers at Mount Sinai School of Medicine in New York, NY, US. The study was presented at the ESC Congress 2012 by principal ...
Cardiology
Aug 27, 2012 |
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BPA link to narrowing of the arteries
A research team from the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, and University of Cambridge has for the first time established a link between high levels of urinary Bisphenol-A (BPA) and ...
Cardiology
Aug 15, 2012 |
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Scientists use worms to unearth cancer drug targets
Through novel experiments involving small nematode worms, scientists from Wyoming have discovered several genes that may be potential targets for drug development in the ongoing war against cancer. Specifically, researchers ...
Cancer
Aug 09, 2012 |
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