News tagged with target genes

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast

Common RNA pathway found in ALS and dementia

Two proteins previously found to contribute to ALS, also known as Lou Gehrig's disease, have divergent roles. But a new study, led by researchers at the Department of Cellular and Molecular Medicine at the University of California, ...

Sep 30, 2012
popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Cold viruses point the way to new cancer therapies

Cold viruses generally get a bad rap—which they've certainly earned—but new findings by a team of scientists at the Salk Institute for Biological Studies suggest that these viruses might also be a valuable ...

Oct 16, 2012
popularity 5 / 5 (5) | comments 0 | with audio podcast

A scanner for hereditary defects

Our genetic material is constantly exposed to damage, which the body's own proteins normally repair. One of these proteins works like a scanner, continually scouring the genetic material for signs of damage. ...

Jan 24, 2013
popularity 4 / 5 (2) | comments 0 | with audio podcast

Evolving genes lead to evolving genes

Researchers have designed a method that can universally test for evolutionary adaption, or positive (Darwinian) selection, in any chosen set of genes, using re-sequencing data such as that generated by the 1000 Genomes Project. ...

Apr 18, 2013
popularity 5 / 5 (1) | comments 0 | with audio podcast