Medical research
A microRNA plays role in major depression
A tiny RNA appears to play a role in producing major depression, the mental disorder that affects as many as 250 million people a year worldwide.
Sep 9, 2016
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News tagged with target genes
Genetics
Broken gene may help protect against ulcerative colitis
We often think of the body as a machine, with every part—right down to each single gene—working with optimal efficiency to keep us healthy and disease-free. Take a single bolt out of that machine and something could go ...
Aug 10, 2016
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Genetics
Study identifies new gene variants that may be targets for treating arrhythmia
Many diseases, such as cancer, diabetes, and schizophrenia, tend to be passed down through families. After researchers sequenced the human genome about 15 years ago, they had high hopes that this trove of information would ...
May 11, 2016
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Neuroscience
Untapped region in brain cell offers goldmine of drug targets for new autism treatments
UCLA scientists have discovered that an overlooked region in brain cells houses a motherlode of mutated genes previously tied to autism. Recently published in Neuron, the finding could provide fresh drug targets and lead ...
Jan 12, 2016
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Parkinson's & Movement disorders
New research sheds light on the molecular origins of Parkinson's disease
As Parkinson's disease progresses in patients, a puzzling dichotomy plays out in their brains. One set of neurons degenerates, while a similar population nearby is spared the same degree of damage. Why the difference? An ...
Aug 10, 2015
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Genetics
Researchers find using genetic association data applied to drug target selection could significantly boost success rate
(Medical Xpress)—A team of researchers with member affiliations to institutions in the U.S. and Hong Kong, has found that researchers going after drug targets that have supporting genetic evidence could double the success ...
Genetics
Study shows connection between key autism risk genes in the human brain
A new study reveals an important connection between dozens of genes that may contribute to autism, a major step toward understanding how brain development goes awry in some individuals with the disorder.
Mar 10, 2015
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Genetics
Type 2 diabetes, cardiovascular disease may share deep roots
(Medical Xpress)—Type 2 diabetes (T2D) and cardiovascular disease (CVD) appear to have a lot in common. They share risk factors such as obesity and they often occur together. If they also share the same genetic underpinings, ...
Nov 4, 2014
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Genetics
Precise gene editing in monkeys paves the way for valuable human disease models
Monkeys are important for modeling diseases because of their close similarities to humans, but past efforts to precisely modify genes in primates have failed. In a study published by Cell Press January 30th in the journal ...
Jan 30, 2014
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Neuroscience
Distinct brain disorders biologically linked
A team of researchers have shown that schizophrenia and a disorder associated with autism and learning difficulties share a common biological pathway. This is one of the first times that researchers have uncovered genetic ...
Aug 4, 2013
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