Oncology & Cancer

Team discovers broken 'brake' of cancer mutation machine

Loss of a gene known as SYNCRIP in prostate cancer tumors unleashes cellular machinery that creates random mutations throughout the genome that drive resistance to targeted treatments, a team led by UT Southwestern Medical ...

Medical research

Study unveils picolinic acid's broad-spectrum antiviral abilities

Picolinic acid, a natural compound produced by mammalian cells, can block several disease-causing viruses such as SARS-CoV-2 and influenza A viruses, according to a new study by researchers at the Indian Institute of Science ...

Medical research

Researchers solve structure of immune-evading HIV protein complex

The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor (Vif). OIST researchers Prof. Matthias Wolf and Dr. Takahide Kouno together with an international team of colleagues have now determined the ...

Immunology

How dendritic cells activate the immune system

The specific or acquired immune system of vertebrates is a powerful weapon against pathogens and pathologically altered body cells. Here, T cells play a special role. After activation, they can systematically kill off target ...

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