Medical research

Team finds key to tuberculosis resistance

The cascade of events leading to bacterial infection and the immune response is mostly understood. However, the molecular mechanisms underlying the immune response to the bacteria that causes tuberculosis have remained a ...

Diseases, Conditions, Syndromes

Tuberculosis avoids and subverts host immunity

An ancient disease, tuberculosis (TB) continues to be one of the major causes of disability and death worldwide. The recent TB cases in Quebec among the Inuit community has underscored the need to find new avenues to eradicate ...

Diseases, Conditions, Syndromes

Drugs to block angiogenesis could provide new treatment for TB

The body responds to tuberculosis infection by locking the bacterial offenders into tiny clusters of immune cells called granulomas, which are a hallmark of the disease. This containment strategy succeeds at first, but eventually ...

Diseases, Conditions, Syndromes

Cochrane Review of RDT for diagnosis of drug resistant TB

Researchers from the Cochrane Infectious Diseases Group, hosted at LSTM, have conducted an independent review to examine the diagnostic accuracy of the GenoType MTBDRsl assay for the detection of resistance to second-line ...

Diseases, Conditions, Syndromes

Shorter tuberculosis treatment not a successful alternative

A clinical drug trial conducted in five Sub-Sahara African countries shows that a shortened (four month) treatment for tuberculosis (TB) is well tolerated and may work well in subsets of TB patients, but overall could not ...

Diseases, Conditions, Syndromes

Boost in quest for TB breath test

A simple breath test may one day show whether someone has a strain of tuberculosis that will respond to a frontline antibiotic, or a drug-resistant type, scientists said Tuesday.

page 7 from 13