News tagged with telomerase enzyme


Researchers identify new potential target for cancer therapy

Researchers at UT Southwestern Medical Center have found that alternative splicing – a process that allows a single gene to code for multiple proteins – appears to be a new potential target for anti-telomerase ...

Cancer created Apr 19, 2013 | popularity 5 / 5 (4) | comments 0 | with audio podcast

Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging

(Medical Xpress)—Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components ...

Medical research created Apr 12, 2013 | popularity 5 / 5 (15) | comments 2 | with audio podcast

Immortality gene mutation identifies brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research ...

Cancer created Mar 18, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Fanning the flames of tumor growth: Enzyme responsible for protecting chromosome ends stimulates tumorigenesis

Chromosomes are capped by long, repetitive DNA sequences called telomeres. These caps prevent genomic damage by insulating against the steady shortening of DNA ends that naturally accompanies replication. ...

Cancer created Feb 27, 2013 | popularity not rated yet | comments 0

Novel technique reveals dynamics of telomere DNA structure

Biomedical researchers studying aging and cancer are intensely interested in telomeres, the protective caps on the ends of chromosomes. In a new study, scientists at UC Santa Cruz used a novel technique to reveal structural ...

Medical research created Jan 17, 2013 | popularity 5 / 5 (2) | comments 0

Researchers uncover new target for cancer research

In a new paper released today in Nature, BioFrontiers Institute scientists at the University of Colorado Boulder, Tom Cech and Leslie Leinwand, detailed a new target for anti-cancer drug development that is sitting at the ...

Cancer created Oct 24, 2012 | popularity 4.8 / 5 (4) | comments 0 | with audio podcast

Telomere failure, telomerase activation drive prostate cancer progression

Genomic instability caused by an erosion of the protective caps on chromosomes, followed by activation of an enzyme that reinforces those caps, allows malignant cells to evade destruction and acquire more deadly characteristics, ...

Cancer created Feb 21, 2012 | popularity 4 / 5 (1) | comments 0

Study in roundworm chromosomes may offer new clues to tumor genome development

A study of DNA rearrangements in roundworm chromosomes may offer new insight into large-scale genome duplications that occur in developing tumors.

Genetics created Apr 21, 2011 | popularity not rated yet | comments 0 | with audio podcast