News tagged with therapeutic agent


Fak inhibitor proves effective against brain tumors in preclinical studies, study shows

(Medical Xpress)—Researchers from Roswell Park Cancer Institute (RPCI) have published findings from a preclinical study assessing the effectiveness of a small-molecule inhibitor, CFAK-Y15, in treating some brain cancers. ...

Cancer created Dec 24, 2012 | popularity not rated yet | comments 0

New immune therapy treats brain tumors in mice

Using an artificial protein that stimulates the body's natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing ...

Immunology created Dec 17, 2012 | popularity 5 / 5 (7) | comments 3 | with audio podcast

Weekly dose reduces targeted drug's side effects, but not its activity against ALL

A potent chemotherapy agent wrapped within a monoclonal antibody selectively destroys the malignant cells responsible for acute lymphocytic leukemia (ALL) in either weekly or monthly dosing, researchers report at the 54th ...

Cancer created Dec 11, 2012 | popularity not rated yet | comments 0

Common heart drug might dampen some autism symptoms

(HealthDay)—A medication typically prescribed to control high blood pressure that's commonly referred to as a water pill may ease some of the symptoms of autism, researchers say.

Autism spectrum disorders created Dec 11, 2012 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Updated clinical results show experimental agent ibrutinib as highly active in CLL patients

Updated results from a Phase Ib/II clinical trial indicates that a novel therapeutic agent for chronic lymphocytic leukemia (CLL) is highly active and well tolerated in patients who have relapsed and are resistant to other ...

Cancer created Dec 09, 2012 | popularity not rated yet | comments 0

American Society of Clinical Oncology issues annual report on state of clinical cancer science

The American Society of Clinical Oncology (ASCO) has just released its annual report on the top cancer advances of the year. Clinical Cancer Advances 2012: ASCO's Annual Report on Progress Against Cancer, highlights major ...

Cancer created Dec 03, 2012 | popularity not rated yet | comments 0

Researchers report first success of targeted therapy in most common non-small cell lung cancer

A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone ...

Cancer created Nov 28, 2012 | popularity not rated yet | comments 0 | with audio podcast

Preclinical muscular dystrophy data shows promise

Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder.

Medical research created Nov 08, 2012 | popularity 4 / 5 (1) | comments 0 | with audio podcast

New targeted therapy for advanced prostate cancer shows anti-tumor activity in clinical trials

Few available treatment options exist once prostate cancer has spread to other parts of the body and has failed to respond to therapies that involve blocking the male hormone androgen. Patients with advanced, hormone-refractory ...

Cancer created Nov 07, 2012 | popularity not rated yet | comments 0

Recent findings may help to fight melanoma's resistance to chemotherapy

Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...

Cancer created Oct 31, 2012 | popularity 1 / 5 (1) | comments 0

Researchers develop new drug delivery system for bladder cancer using nanoparticles

A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, ...

Cancer created Oct 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

USADA's chief science officer publishes editorial on anti-dope testing in sport: History and science

Lance Armstrong's doping scandal may be considered by U.S. Anti-Doping Agency (USADA) as "more extensive than any previously revealed in professional sports history," but a new editorial in The FASEB Journal by USADA's Larry ...

Other created Oct 12, 2012 | popularity not rated yet | comments 0

Anti-cancer drug fights immune reaction in some infants with Pompe disease

Adding a third anti-cancer agent to a current drug cocktail appears to have contributed to dramatic improvement in three infants with the most severe form of Pompe disease—a rare, often-fatal genetic disorder ...

Genetics created Oct 11, 2012 | popularity 3.5 / 5 (2) | comments 0

Monoclonal antibody effective therapy for diabetic retinopathy

(HealthDay)—An antibody can reduce retinal vascular leakage and inflammation in rat models of diabetic retinopathy, according to a study published online Oct. 1 in Diabetes.

Diabetes created Oct 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

MRI images transplanted islet cells with help of positively charged nanoparticles

In a study to investigate the detection by MRI of six kinds of positively-charged magnetic iron oxide nanoparticles designed to help monitor transplanted islet cells, a team of Japanese researchers found that the charged ...

Medical research created Oct 01, 2012 | popularity not rated yet | comments 0