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News tagged with therapeutic agents


New immune therapy treats brain tumors in mice

Using an artificial protein that stimulates the body's natural immune system to fight cancer, a research team at Duke Medicine has engineered a lethal weapon that kills brain tumors in mice while sparing ...

Immunology created Dec 17, 2012 | popularity 5 / 5 (7) | comments 3 | with audio podcast

Compound that could prevent acute blood cancer relapse identified

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan report today that they have identified a compound that could be used as a new treatment to prevent relapse in acute myeloid leukemia patients.

Cancer created Apr 17, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Stem cells found to heal damaged artery in lab study

Scientists at the Texas Biomedical Research Institute have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise ...

Medical research created Jan 10, 2013 | popularity 5 / 5 (2) | comments 0 | with audio podcast

Novel intercellular transportation system may have potential for delivering RNAi and other gene-based therapeutics

(Medical Xpress)—Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting ...

Neuroscience created Mar 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Study points to potential treatment for stroke

Stanford University School of Medicine neuroscientists have demonstrated, in a study to be published online April 24 in Stroke, that a compound mimicking a key activity of a hefty, brain-based protein is capable of increa ...

Cardiology created Apr 24, 2012 | popularity not rated yet | comments 0 | with audio podcast

Team mimicking a natural defense against malaria to develop new treatments

(Medical Xpress)—One of the world's most devastating diseases is malaria, responsible for at least a million deaths annually, despite global efforts to combat it.  Researchers from the Perelman School ...

Medical research created Dec 27, 2012 | popularity 5 / 5 (2) | comments 1 | with audio podcast

Peptides for the treatment of severe diseases

A new class of drugs for the treatment of severe diseases such as cancer and autoimmune diseases is developed by the start-up Bicycle Therapeutics. The company is generating bicyclic peptides that can selectively ...

Medical research created Apr 15, 2013 | popularity 5 / 5 (1) | comments 0

Engineered bacteria effectively target tumors, enabling tumor imaging potential in mice

Tumor-targeted bioluminescent bacteria have been shown for the first time to provide accurate 3D images of tumors in mice, further advancing the potential for targeted cancer drug delivery, according to a ...

Cancer created Jan 25, 2012 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Monoclonal antibody effective therapy for diabetic retinopathy

(HealthDay)—An antibody can reduce retinal vascular leakage and inflammation in rat models of diabetic retinopathy, according to a study published online Oct. 1 in Diabetes.

Diabetes created Oct 07, 2012 | popularity not rated yet | comments 0 | with audio podcast

Study points to essential role of IL-22 in lung repair after the flu

Once the initial episode of influenza has passed, the chronic effects tend to be overlooked. The results of a new study indicate that the cytokine interleukin-22 (IL-22) plays a critical role in normal lung repair following ...

Medical research created Mar 11, 2013 | popularity not rated yet | comments 0

Study shows mirabegron effective and well tolerated for overactive bladder

In a new phase III trial mirabegron, a β3-adrenoceptor agonist, given once daily for 12 weeks, reduced the frequency of incontinence episodes and number of daily urinations, and improved urgency and nocturia in adults with ...

Diseases, Conditions, Syndromes created Mar 04, 2013 | popularity not rated yet | comments 0

Engineered oncolytic herpes virus inhibits ovarian and breast cancer metastases

A genetically reprogrammed Herpes simplex virus (HSV) can cure metastatic diffusion of human cancer cells in the abdomen of laboratory mice, according to a new study published January 31 in the Open Access journal PLOS Pa ...

Cancer created Jan 31, 2013 | popularity 5 / 5 (3) | comments 1

Naturally occurring substance proves effective against deadly skin cancer in laboratory tests

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin ...

Cancer created Apr 10, 2013 | popularity 5 / 5 (1) | comments 0

Mechanism of smoking-induced insulin resistance elucidated

(HealthDay)—Smoking-induced insulin resistance, which improves with smoking cessation, may be due to activation of mammalian target of rapamycin (mTOR), according to a study published online Sept. 10 in ...

Diabetes created Sep 17, 2012 | popularity 5 / 5 (1) | comments 0

Propping open the door to the blood brain barrier

The treatment of central nervous system (CNS) diseases can be particularly challenging because many of the therapeutic agents such as recombinant proteins and gene medicines are not easily transported across the blood-brain ...

Medical research created Feb 01, 2013 | popularity not rated yet | comments 0