News tagged with therapeutic drug


Mice with 'humanized' livers improve early drug testing

Stanford University School of Medicine scientists have used bioengineered mice with livers composed largely of human cells to characterize a drug about to enter early-stage clinical development for combating hepatitis C.

Medical research created Oct 31, 2012 | popularity 3 / 5 (1) | comments 0 | with audio podcast

Recent findings may help to fight melanoma's resistance to chemotherapy

Blocking the action of a particular protein in our skin could improve the treatment of skin cancers, according to a study published in Oncogene yesterday by Philippe Roux, a researcher at the University of Montreal's Instit ...

Cancer created Oct 31, 2012 | popularity 1 / 5 (1) | comments 0

Canadian scientists discover cause of high cholesterol

Canadian scientists have discovered that a protein called resistin, secreted by fat tissue, causes high levels of "bad" cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease.

Medical research created Oct 28, 2012 | popularity 3 / 5 (1) | comments 0

Researchers develop new drug delivery system for bladder cancer using nanoparticles

A team of UC Davis scientists has shown in experimental mouse models that a new drug delivery system allows for administration of three times the maximum tolerated dose of a standard drug therapy for advanced bladder cancer, ...

Cancer created Oct 25, 2012 | popularity not rated yet | comments 0 | with audio podcast

Meningitis victims face long, uncertain recovery

(AP)—Vilinda York lies in her Florida hospital bed, facing a dry-erase board that lists in green marker her name, her four doctors and a smiley face.

Diseases, Conditions, Syndromes created Oct 20, 2012 | popularity not rated yet | comments 1

Proteins in DNA damage response network targeted for new therapies, researchers say

(Medical Xpress)—Researchers at Moffitt Cancer Center and colleagues at the University of South Florida; Duke University; Johns Hopkins University; the Brazilian National Cancer Institute; and the Rio de Janeiro Federal ...

Medical research created Oct 16, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

USADA's chief science officer publishes editorial on anti-dope testing in sport: History and science

Lance Armstrong's doping scandal may be considered by U.S. Anti-Doping Agency (USADA) as "more extensive than any previously revealed in professional sports history," but a new editorial in The FASEB Journal by USADA's Larry ...

Other created Oct 12, 2012 | popularity not rated yet | comments 0

Anti-cancer drug fights immune reaction in some infants with Pompe disease

Adding a third anti-cancer agent to a current drug cocktail appears to have contributed to dramatic improvement in three infants with the most severe form of Pompe disease—a rare, often-fatal genetic disorder ...

Genetics created Oct 11, 2012 | popularity 3.5 / 5 (2) | comments 0

Prospective Alzheimer's drug builds new brain cell connections

Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment.

Alzheimer's disease & dementia created Oct 11, 2012 | popularity 5 / 5 (8) | comments 7 | with audio podcast

Healthcare professionals as bad as patients at good respiratory inhaler technique

Healthcare professionals are as bad as patients when it comes to knowing how to use inhalers prescribed for asthma and other respiratory conditions correctly, says an editorial in Drug and Therapeutics Bulletin (DTB).

Diseases, Conditions, Syndromes created Oct 03, 2012 | popularity not rated yet | comments 0

New evidence on easing inflammation of brain cells for Alzheimer's disease

New research proves the validity of one of the most promising approaches for combating Alzheimer's disease (AD) with medicines that treat not just some of the symptoms, but actually stop or prevent the disease ...

Alzheimer's disease & dementia created Oct 03, 2012 | popularity 5 / 5 (1) | comments 0

Study adds to efforts to find more effective anti-inflammatory drugs

Researchers have discovered a previously unknown function for a protein that could add to the expanding arsenal of potential new drugs for battling inflammation and tissue fibrosis in a number of disease processes.

Inflammatory disorders created Sep 27, 2012 | popularity not rated yet | comments 0 | with audio podcast

Discovery may shed light on why some HIV-positive patients have more virus

(Medical Xpress)—Biologists at UC San Diego have unraveled the anti-viral mechanism of a human gene that may explain why some people infected with HIV have much higher amounts of virus in their bloodstreams ...

HIV & AIDS created Sep 24, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Biomarkers for antidepressant treatment response

(Medical Xpress)—Researchers from King's College London's Institute of Psychiatry (IoP) have identified new biomarkers for antidepressant treatment response, an important step towards developing personalised ...

Psychology & Psychiatry created Sep 20, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genetically-engineered preclinical models predict pharmacodynamic response

New cancer drugs must be thoroughly tested in preclinical models, often in mice, before they can be offered to cancer patients for the first time in phase I clinical trials. Key components of this process include pharmacokinetic ...

Cancer created Sep 19, 2012 | popularity not rated yet | comments 0 | with audio podcast