News tagged with therapeutic effect


Effect of fluid and sodium restrictions on weight loss among patients with heart failure

A clinical trial of 75 patients hospitalized with acute decompensated heart failure (ADHF) suggests that aggressive fluid and sodium restriction has no effect on weight loss or clinical stability at three days but was associated ...

Cardiology created May 20, 2013 | popularity not rated yet | comments 0

Gene variant appears to predict weight loss after gastric bypass

Massachusetts General Hospital (MGH) researchers have identified a gene variant that helps predict how much weight an individual will lose after gastric bypass surgery, a finding with the potential both to ...

Genetics created May 02, 2013 | popularity not rated yet | comments 0 | with audio podcast

Study shines light on how stress circuits learn

Researchers at the University of Calgary's Hotchkiss Brain Institute have discovered that stress circuits in the brain undergo profound learning early in life. Using a number of cutting edge approaches, including ...

Neuroscience created Apr 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Novel intercellular transportation system may have potential for delivering RNAi and other gene-based therapeutics

(Medical Xpress)—Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting ...

Neuroscience created Mar 27, 2013 | popularity 5 / 5 (3) | comments 0 | with audio podcast

Beyond Botox: Natural born killer or medical miracle?

Botox is best known for its use in cosmetic procedures, but this potent neurotoxin could be transformed into an extraordinary drug to treat a raft of debilitating conditions, a leading scientist will tell ...

Medical research created Mar 15, 2013 | popularity 5 / 5 (1) | comments 0

Japanese P2 study shows potential of combined vaccine and steroid drug in castration resistant PCa

Multi-peptide vaccination therapy combined with the low-dose steroid drug dexamethasone shows promise in treating chemotherapy-naive castration resistant prostate cancer (CRPC) patients.

Cancer created Mar 15, 2013 | popularity not rated yet | comments 0

Study identifies growth factor essential to the most common malignant pediatric brain tumor

A multi-institutional team led by Massachusetts General Hospital (MGH) researchers has identified a molecular pathway that appears to be essential for the growth and spread of medulloblastoma, the most common ...

Cancer created Feb 28, 2013 | popularity not rated yet | comments 0 | with audio podcast

Drug delivery strategy eliminates myotonia symptoms in mice with myotonic dystrophy

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms ...

Diseases, Conditions, Syndromes created Feb 22, 2013 | popularity 5 / 5 (1) | comments 0

Cure in sight for kissing bug's bite

Chagas disease, a deadly tropical infection caused by the protozoan parasite Trypanosoma cruzi and transmitted by biting insects called "kissing bugs," has begun to spread around the world, including the U.S. Yet current treatm ...

Medications created Feb 14, 2013 | popularity not rated yet | comments 0

Sublingual immunotherapy shows promise as treatment for peanut allergy

Peanuts are one of the most common triggers of severe food-induced allergic reactions, which can be fatal, and the prevalence of peanut allergy is increasing. However, there is currently no clinical treatment available for ...

Immunology created Jan 07, 2013 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Alzheimer's-plagued Colombia region is focus of drug trial

The unusually high incidence of early-onset Alzheimer's disease in this isolated cattle town has thrust it to the forefront of global efforts to find a cure for the debilitating malady.

Alzheimer's disease & dementia created Dec 17, 2012 | popularity not rated yet | comments 0

Better understanding of the cause of Alzheimer's disease: New suggestion for a possible treatment

Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aß) protein causes neuronal loss in patients. Medication focuses ...

Alzheimer's disease & dementia created Dec 14, 2012 | popularity not rated yet | comments 0

Despite hype, costly prostate cancer treatment offers little relief from side effects

Prostate cancer patients receiving the costly treatment known as proton radiotherapy experienced minimal relief from side effects such as incontinence and erectile dysfunction, compared to patients undergoing a standard radiation ...

Cancer created Dec 13, 2012 | popularity not rated yet | comments 0 | with audio podcast

Genome-scale study identifies hundreds of potential drug targets for Huntington's disease

Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...

Genetics created Nov 29, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast

Double duty: Immune system regulator found to protect brain from effects of stroke

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how ...

Immunology created Nov 28, 2012 | popularity 5 / 5 (1) | comments 0 | with audio podcast