A gene therapeutic approach that shows promise for treating age-related macular degeneration (AMD) may also be effective in treating other eye conditions such as glaucoma. It provided benefit in three additional models of ...
Jan 30, 2023
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11
Many cardiovascular diseases, such as atherosclerosis, or "hardening of the arteries," correlate to mitochondrial dysfunction and endothelial impairment in the tissues of the heart and blood vessels. Despite a significant ...
Jan 24, 2023
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17
The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and demonstrated their use for quantitative ...
Jan 12, 2023
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28
A research group led by CiRA Junior Associate Professor Kazuo Takayama and Associate Professor Yoshiaki Okada of Osaka University has revealed that SARS-CoV-2 disrupts the vascular endothelial barrier by suppressing the expression ...
Sep 28, 2022
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71
Swiss pharmaceuticals company Novartis said Thursday that it plans to spin off its generics subsidiary Sandoz, which generated nearly $10 billion in revenue last year.
Aug 25, 2022
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17
As SARS-CoV-2 has evolved and mutated, therapeutic antibodies that worked early in the pandemic have become less effective, and newer variants, especially omicron, have developed ways to evade the antibodies we make in response ...
Aug 11, 2022
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170
The tumor biomarker research team from the Suzhou Institute of Biomedical Engineering and Technology of the Chinese Academy of Sciences recently reported that DMDRMR/miR-378a-5p/ DAB2IP axis promotes angiogenesis and sunitinib ...
May 25, 2022
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Delivered using adenovirus (Ad) vectors, therapeutic genes address the cause of disease—not just the symptoms. However, while advances in the understanding of human diseases and the genome have led to an increasing number ...
May 11, 2022
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17
Nucleic acid therapeutics, which involve transferring exogenous genes inside target cells, are a promising clinical treatment option that can regulate gene expression at the transcriptional or post-transcriptional level.
May 5, 2022
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Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus ...
Apr 1, 2022
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