News tagged with therapeutic target
Related topics: cancer cells , protein , mouse model , cancer , breast cancer
The factor that could influence future breast cancer treatment
Australian scientists have shown in the laboratory how a 'transcription factor' causes breast cancer cells to develop an aggressive subtype that lacks sensitivity to estrogen and does not respond to known anti-estrogen therapies. ...
Cancer
Dec 27, 2012 |
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Three new genetic links to colorectal cancer
Vanderbilt-Ingram Cancer Center investigators have identified three new genetic "hotspots" linked to colorectal cancer. These variants, reported Dec. 23 in an Advanced Online Publication in Nature Genetics, provide new in ...
Cancer
Dec 23, 2012 |
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Serendipity points to new potential target and therapy for melanoma
(Medical Xpress)—A University of Colorado Cancer Center study in this month's edition of the Journal of Investigative Dermatology describes a new target and potential treatment for melanoma, the most d ...
Cancer
Dec 20, 2012 |
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Removing protein 'garbage' in nerve cells may help control two neurodegenerative diseases
Neuroscientists at Georgetown University Medical Center say they have new evidence that challenges scientific dogma involving two fatal neurodegenerative diseases—amyotrophic lateral sclerosis (ALS), and frontotemporal ...
Medical research
Dec 20, 2012 |
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New research discovery provides therapeutic target for ALS
Research led by Dr. Udai Pandey, Assistant Professor of Genetics at LSU Health Sciences Center New Orleans, has found that the ability of a protein made by a gene called FUS to bind to RNA is essential to the development ...
Genetics
Dec 19, 2012 |
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Harnessing the ID in glioma
Gliomas are the most common form of brain tumor. They are highly aggressive and effective treatments are not currently available. The tumors contain glioma initiating cells (GICs), a population that is highly similar to neural ...
Cancer
Dec 17, 2012 |
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Study reveals alternative pathway through which beta-catenin drives colon cancer
Colon cancer is one of the leading causes of cancer-related death in the United States. Risk factors for the disease are varied and include factors such as advanced age and diet, but most cases share something ...
Cancer
Dec 14, 2012 |
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Scientists identify new biomarker for cancer in bone marrow: Promise for patients of multiple myeloma
Singapore scientists have identified FAIM, a molecule that typically prevents cell death, as a potential biomarker to identify an incurable form of cancer in the bone marrow. Patients with this form of cancer usually do not ...
Cancer
Dec 13, 2012 |
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Weekly dose reduces targeted drug's side effects, but not its activity against ALL
A potent chemotherapy agent wrapped within a monoclonal antibody selectively destroys the malignant cells responsible for acute lymphocytic leukemia (ALL) in either weekly or monthly dosing, researchers report at the 54th ...
Cancer
Dec 11, 2012 |
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Novel drug therapy targets aggressive form of non-Hodgkin's lymphoma
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin's lymphoma and the seventh most frequently diagnosed cancer. The most chemotherapy resistant form of DLBCL, called activated B-cell – DLBCL ...
Cancer
Dec 10, 2012 |
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TGen-US Oncology data guides treatment of metastatic triple-negative breast cancer patients
Genomic sequencing has revealed therapeutic drug targets for difficult-to-treat, metastatic triple-negative breast cancer (TNBC), according to an unprecedented study by the Translational Genomic Research Institute (TGen) ...
Cancer
Dec 06, 2012 |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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Researchers report first success of targeted therapy in most common non-small cell lung cancer
A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone ...
Cancer
Nov 28, 2012 |
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Scientists uncover a novel cooperative effort to stop cancer spread
(Medical Xpress)—Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the ...
Cancer
Nov 28, 2012 |
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The placebo effect goes beyond humans, researchers find
(Medical Xpress)—Rats and humans have at least one thing in common: They both react the same way to a placebo, according to a new University of Florida study.
Medical research
Nov 28, 2012 |
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