Stem-cell-based strategy boosts immune system in mice
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, ...
Immunology
May 16, 2013 |
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Separate lives: Neuronal and organismal lifespans decoupled
(Medical Xpress)—Replicative aging (also known as replicative senescence) causes mammalian cells to undergo a process of growth arrest dependent on telomeres (the shortening of repeated sequences at the ends o ...
Neuroscience
Mar 27, 2013 |
4.9 / 5 (8) |
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Thymus teaches immune cells to ignore vital gut bacteria
The tiny thymus teaches the immune system to ignore the teeming, foreign bacteria in the gut that helps you digest and absorb food, researchers say.
Immunology
Apr 29, 2013 |
4.7 / 5 (3) |
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Live from the thymus: T-cells on the move
T-cells are the immune system's security force. They seek out pathogens and rogue cells in the body and put them out of action. Their precursors are formed in the bone marrow and migrate from there into the ...
Medical research
Feb 17, 2012 |
4.5 / 5 (2) |
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Immune system uses heart channel to select powerful defenders
(Medical Xpress) -- When the body makes immune T cells, it relies on a molecular channel more commonly seen in nerves and heart muscles to ensure that the powerful T cells have the right mixture of aggressiveness ...
Immunology
Aug 16, 2012 |
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Penn researchers describe key molecule that keeps immune cell development on track
In the latest issue of Nature, researchers at the Perelman School of Medicine at the University of Pennsylvania clarify the role of two proteins key to T-cell development. They found that one well-known protein called Notch ...
Medical research
Aug 08, 2011 |
4 / 5 (1) |
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Lipids produced within the thymus give immune cells the initial boost they need to fight off infection
Semi-invariant natural killer T (iNKT) cells wage war against infectious threats, attacking microbial cells and generating signals that enable other immune cells also to respond aggressively. iNKT cells initially ...
Immunology
Sep 12, 2012 |
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Tonsils make T cells, too, study shows
A new study provides evidence that a critical type of immune cell can develop in human tonsils. The cells, called T lymphocytes, or T cells, have been thought to develop only in the thymus, an organ of the immune system that ...
Medical research
Mar 05, 2012 |
4.7 / 5 (3) |
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'Personalized immune' mouse offers new tool for studying autoimmune diseases
Columbia University Medical Center (CUMC) scientists have developed a way to recreate an individual's immune system in a mouse. The "personalized immune mouse" offers researchers an unprecedented tool for individualized analysis ...
Immunology
Mar 14, 2012 |
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Scientists discover special class of natural fats stimulates immune cells to fight diseases
An international research team led by scientists from Singapore Immunology Network (SIgN) under the Agency of Science, Technology and Research (A*STAR) discovered that a special class of fatty molecules is essential for activating ...
Immunology
Apr 02, 2012 |
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Vitamin D analogs modulate immunity in psoriasis
(HealthDay) -- Vitamin D3 analogs modulate immunity in human psoriasis, inducing thymic stromal lymphopoietin (TSLP) and cathelicidin, according to a study published online March 2 in the British Journal of ...
Diseases, Conditions, Syndromes
Mar 09, 2012 |
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Adult congenital heart patients with highest surgery costs more likely to die in hospital
Higher surgical costs for adult congenital heart patients is associated with higher rates of inpatient death compared to surgical admissions that incur lower costs, according to a study in Circulation: Quality and Outcomes, a jour ...
Cardiology
Oct 18, 2011 |
5 / 5 (1) |
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Artificial thymus tissue enables maturation of immune cells
The thymus plays a key role in the body's immune response. It is here where the T lymphocytes or T cells, a major type of immune defence cells, mature. Different types of T cells, designated to perform specific ...
Immunology
Mar 29, 2012 |
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A new clue to predicting pre-eclampsia
(Medical Xpress) -- An indication of whether a mother will develop pre-eclampsia, the most common and severe pregnancy-related disease, has been identified by a University of Sydney study.
Immunology
May 09, 2012 |
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