New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons. The work provides ...
Feb 27, 2020
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A synthetic small molecule compound called AQAMAN can prevent and even reverse harmful protein build-up in neurons that is associated with several rare neurodegenerative disorders, including polyglutamine (or polyQ) diseases.
Jan 10, 2020
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A new vaccine developed by Griffith University Institute for Glycomics researchers has the potential to treat and prevent toxic shock caused by invasive streptococcal disease, which kills more than 160,000 people every year.
Sep 4, 2019
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A toxic protein linked to Huntington's disease can move from neuron to neuron through a nanotube tunnel whose construction is initiated by a protein called Rhes, say scientists at Scripps Research.
May 10, 2019
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One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...
Mar 1, 2019
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Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in ...
Feb 8, 2019
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Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...
Jan 22, 2019
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Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2). IL-2 is a potent anticancer drug and ...
Jan 9, 2019
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A research team led by Professor Sung Bae Lee of Brain and Cognitive Sciences and Professor Daehee Hwang of New Biology (vice-head of the Plant Age and Life Research Group, IBS) has identified the early neuropathological ...
Jan 7, 2019
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Some neurons in the brain protect themselves from Alzheimer's with a cellular cleaning system that sweeps away toxic proteins associated with the disease, according to a new study from Columbia University and the University ...
Dec 17, 2018
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