The viral replication cycle is crucial for a virus to spread inside the body and cause disease. Focusing on that cycle in the hepatitis A virus (HAV), UNC School of Medicine scientists discovered that replication requires ...
Jul 4, 2022
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Scientists at UW Medicine's Institute for Protein Design (IPD) in Seattle have created a new protein that mimics the action of a key immune regulatory protein, interleukin 2 (IL-2). IL-2 is a potent anticancer drug and ...
Jan 9, 2019
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232
One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...
Mar 1, 2019
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UC Davis researchers have found novel compounds that disrupt the formation of amyloid, the clumps of protein in the brains of people with Alzheimer's disease believed to be important in causing the disease's characteristic ...
Apr 30, 2012
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Tufts researchers are building a reputation for precision targeting in drug delivery. Their tools: tiny lipid-based nanoparticles (LNPs) fine-tuned to latch on to specific tissues, organs, even cell types within the body. ...
Feb 23, 2022
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The recent ability to peer into the brain of living individuals with a rare type of language dementia, primary progressive aphasia (PPA), provides important new insights into the beginning stages of this disease—which results ...
Mar 7, 2016
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New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons. The work provides ...
Feb 27, 2020
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A new study found no evidence to support concerns that abnormal neurodegenerative disease proteins are "infectious" or transmitted from animals to humans or from one person to another.
Feb 4, 2013
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A "perfect storm" of genetic mutations, toxic proteins and a defect in natural cell recycling has been uncovered in University of Queensland research that could lead to treatments for neurodegenerative diseases such as Alzheimer's ...
Jul 8, 2021
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25
Researchers have gained insight into how a toxic protein, known to trigger muscular dystrophy, could be deactivated—a pre-clinical discovery that could spearhead a treatment for the debilitating disease.
Sep 25, 2023
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