Of enzymes and aging: Tryptophan metabolism plays key role in aging and age-related neurological diseases
(Medical Xpress)—In the battle against aging and age-related neurological diseases such as Parkinson's and Alzheimer's, a key factor has long appeared to be the toxicity of proteins which tend to aggregate. ...
Medical research
Oct 05, 2012 |
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Researchers report potential new treatment to stop Alzheimer's disease
Last March, researchers at UCLA reported the development of a molecular compound called CLR01 that prevented toxic proteins associated with Parkinson's disease from binding together and killing the brain's neurons.
Alzheimer's disease & dementia
Nov 15, 2012 |
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Cell contents may be key to controlling toxicity of Huntington's disease protein
New research into the cell-damaging effects of Huntington's disease suggests a potentially new approach for identifying possible therapeutic targets for treating the nerve-destroying disorder.
Genetics
Jun 06, 2012 |
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Scientists boost potency, reduce side effects of IL-2 protein used to treat cancer
The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist ...
Medical research
Mar 18, 2012 |
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Cancer drug prevents build-up of toxic brain protein
Researchers at Georgetown University Medical Center have used tiny doses of a leukemia drug to halt accumulation of toxic proteins linked to Parkinson's disease in the brains of mice. This finding provides the basis to plan ...
Genetics
May 10, 2013 |
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Scientists discover new target for personalized cancer therapy
A common cancer pathway causing tumor growth is now being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine have developed a ...
Cancer
May 02, 2013 |
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Science surprise: Toxic protein made in unusual way may explain brain disorder
A bizarre twist on the usual way proteins are made may explain mysterious symptoms in the grandparents of some children with mental disabilities.
Neuroscience
Apr 18, 2013 |
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Research team uncovers shape of transmembrane protein partly responsible for antibiotic resistance
(Medical Xpress)—Researchers from the University of Tokyo have uncovered the physical layout of a transmembrane protein that the tiny organism Archaea relies on to keep toxins out of its cells. The protein, ...
Medical research
Mar 28, 2013 |
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From shape-shifting to therapy
(Medical Xpress)—The latest research into the intricate processes that let substances into and out of cells will help to lay the foundations for the next generation of therapies for major diseases.
Medical research
Mar 12, 2013 |
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Researchers find new way of killing leukaemia cells
(Medical Xpress)—Researchers at the University of Dundee have identified a new way of killing cancer cells in patients with a certain kind of leukaemia, which could lead to the development of safer anti-leukaemic drugs.
Cancer
Mar 04, 2013 |
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Research finds protein that prevents light-induced retinal degeneration
Research led by Minghao Jin, PhD, Assistant Professor of Ophthalmology and Neuroscience at the LSU Health Sciences Center New Orleans Neuroscience Center of Excellence, has found a protein that protects retinal photoreceptor ...
Neuroscience
Feb 12, 2013 |
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Study confirms no transmission of Alzheimer's proteins between humans
A new study found no evidence to support concerns that abnormal neurodegenerative disease proteins are "infectious" or transmitted from animals to humans or from one person to another.
Alzheimer's disease & dementia
Feb 04, 2013 |
3.7 / 5 (3) |
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Poison for cancer cells: New method identifies active agents in mixtures of hundreds of substances
In their quest for new agents, pharmaceutical researchers test millions of substances all over the world. They like using color-forming reactions to identify new molecules. However, in intensively colored ...
Cancer
Dec 20, 2012 |
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Novel antibodies for combating Alzheimer's and Parkinson's disease
Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, ...
Neuroscience
Dec 03, 2012 |
4 / 5 (2) |
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Genome-scale study identifies hundreds of potential drug targets for Huntington's disease
Scientists searching for ways to develop treatments for Huntington's disease (HD) just got a roadmap that could dramatically speed their discovery process. Researchers at the Buck Institute have used RNA interference (RNAi) ...
Genetics
Nov 29, 2012 |
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