A synthetic small molecule compound called AQAMAN can prevent and even reverse harmful protein build-up in neurons that is associated with several rare neurodegenerative disorders, including polyglutamine (or polyQ) diseases.
Jan 10, 2020
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One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease – referred to as non-alcoholic fatty liver disease (NAFLD) – causes no symptoms initially ...
Mar 1, 2019
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Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in ...
Feb 8, 2019
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Patients with ALS frequently have a string of repeated DNA code in the cells of their brain, carrying hundreds to thousands of copies within the gene C9orf72. New research looks at what triggers these repeated sequences to ...
Jan 22, 2019
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A research team led by Professor Sung Bae Lee of Brain and Cognitive Sciences and Professor Daehee Hwang of New Biology (vice-head of the Plant Age and Life Research Group, IBS) has identified the early neuropathological ...
Jan 7, 2019
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A new variant of the gene-editing CRISPR/Cas9 system is safer and more specific than versions previously used in early research towards a treatment for Huntington's disease, shows research published today in Frontiers in ...
Feb 26, 2018
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A study by a group of researchers including those from The Montreal Neurological Institute and Hospital of McGill University has tested the theory that brain degeneration in Parkinson's disease (PD) originates in subcortical ...
Jan 12, 2018
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Researchers have found cell receptors abnormally overexpressed in post-mortem brains of those with Parkinson's and Alzheimer's diseases, and that they can be inhibited in animal models to clear toxic protein buildup, reduce ...
Jul 16, 2017
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Two new treatments are showing promise and overall survival is on the rise for AL amyloidosis, according to a series of studies involving researchers in the Abramson Cancer Center and the Perelman School of Medicine at the ...
Dec 1, 2016
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A new study from The University of Texas Medical Branch at Galveston offers important insight into how Alzheimer's disease begins within the brain. The researchers found a relationship between inflammation, a toxic protein ...
Nov 18, 2016
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