News tagged with transcription factors
Related topics: genes , cells , gene expression , stem cells , dna sequences
Protein may represent a switch to turn off B cell lymphoma
Researchers studying the molecular signals that drive a specific type of lymphoma have discovered a key biological pathway leading to this type of cancer. Cancerous cells have been described as being "addicted" to certain ...
Cancer
May 07, 2012 |
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Study confirms genetic predictor for Fuchs' corneal dystrophy
Mayo Clinic and University of Oregon researchers have confirmed that a genetic factor called a repeating trinucleotide is a strong predictor of an individual's risk of developing the eye condition Fuchs' dystrophy. The findings ...
Ophthalmology
May 07, 2012 |
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Scientists uncover liver's role in preventing dissemination of lung infection
Researchers at Boston University School of Medicine (BUSM) have discovered the regulation and functional significance of the acute phase response during a lung infection. The findings, which will be published in the May edition ...
Medical research
Apr 02, 2012 |
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Smokers could be more prone to schizophrenia, study finds
Smoking alters the impact of a schizophrenia risk gene. Scientists from the universities of Zurich and Cologne demonstrate that healthy people who carry this risk gene and smoke process acoustic stimuli in a similarly deficient ...
Diseases, Conditions, Syndromes
Mar 26, 2012 |
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New compound discovered that rapidly kills liver cancer
Scientists have identified a new compound that rapidly kills hepatocellular carcinoma (HCC) cells, the most common form of liver cancer and fifth most common cancer worldwide, while sparing healthy tissue. The compound, Factor ...
Cancer
Mar 14, 2012 |
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Scientists discover primitive gut's role in left-right patterning
Scientists have found that the gut endoderm has a significant role in propagating the information that determines whether organs develop in the stereotypical left-right pattern. Their findings are published 6 March 2012 in ...
Medical research
Mar 06, 2012 |
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No workout? No worries: Scientists prevent muscle loss in mice, despite disease and inactivity
If you want big muscles without working out, there's hope. In the March 2012 print issue of the FASEB Journal, scientists from the University of Florida report that a family of protein transcription factors, called "Forkhead (F ...
Medical research
Feb 29, 2012 |
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A two-pronged attack: Why loss of STAT1 is bad news
Breast cancer represents about a fifth of all cancers diagnosed in women. The reasons for the rapid progression of the disease remain relatively poorly understood but recent work in the group of Veronika Sexl at the University ...
Cancer
Feb 29, 2012 |
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Scientists collaborate in discovery of new targets for the treatment of asthma
A collaboration between scientists in Trinity College Dublin and the United Kingdom has identified new processes that lead to the development of a novel cell implicated in allergies. The discovery has the potential for new ...
Immunology
Feb 27, 2012 |
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UK study provides insight into cancer progression
The University of Kentucky has announced that Dr. Daret St. Clair, the James Graham Brown Endowed Chair and professor of toxicology, has published the first comprehensive study that provides insight into the relationship ...
Cancer
Feb 22, 2012 |
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Researchers find important 'target' playing role in tobacco-related lung cancers
Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce ...
Cancer
Feb 09, 2012 |
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CD97 gene expression and function correlate with WT1 protein expression and glioma invasiveness
Researchers at Virginia Commonwealth University Medical Center's VCU Massey Cancer Center and Harold F. Young Neurosurgical Center (Richmond, VA) and Old Dominion University (Norfolk, VA) have discovered that suppression ...
Neuroscience
Feb 07, 2012 |
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SUMO-snipping protein plays crucial role in T and B cell development
When SUMO grips STAT5, a protein that activates genes, it blocks the healthy embryonic development of immune B cells and T cells unless its nemesis breaks the hold, a research team led by scientists at The University of Texas ...
Genetics
Jan 27, 2012 |
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'DIMming' cancer growth -- STAT: Diindolylmethane suppresses ovarian cancer
Ovarian cancer is a major cause of death worldwide. Approximately 25,000 women will be diagnosed with ovarian cancer this year and 15,000 women will die from it in the United States alone. The novel anti-cancer drug diindolylmethane ...
Cancer
Jan 26, 2012 |
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Research team discovers genes and disease mechanisms behind a common form of muscular dystrophy
Continuing a series of groundbreaking discoveries begun in 2010 about the genetic causes of the third most common form of inherited muscular dystrophy, an international team of researchers led by a scientist at Fred Hutchinson ...
Cancer
Jan 12, 2012 |
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