News tagged with transcription factors
Related topics: genes , cells , gene expression , stem cells , dna sequences
Signaling to chromatin
(Medical Xpress) -- Scientists from the Friedrich Miescher Institute for Biomedical Research (FMI) in collaboration with their colleagues from the Department of Biosystems Science and Engineering of the ETH ...
Genetics
Jan 03, 2012 |
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Mutation in gene that's critical for human development linked to arrhythmia
Arrhythmia is a potentially life-threatening problem with the rate or rhythm of the heartbeat, causing it to go too fast, too slow or to beat irregularly. Arrhythmia affects millions of people worldwide.
Genetics
Dec 27, 2011 |
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Researchers identify agent responsible for protection against early stages of atherosclerosis
Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in ...
Cardiology
Dec 12, 2011 |
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Illuminating cross talk between signalling factors
(Medical Xpress) -- Hypoxia and inflammation are environmental features occuring simultaneously in a variety of diseases such as growing tumours and critically inflamed tissues. UCD scientists investigating the relative contributions ...
Medical research
Nov 22, 2011 |
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Newly identified gene mutation adds to melanoma risk
A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer. The identified mutation occurs ...
Cancer
Nov 13, 2011 |
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Non-coding RNA relocates genes when it's time to go to work
Cells develop and thrive by turning genes on and off as needed in a precise pattern, a process known as regulated gene transcription. In a paper published in the Nov. 9 issue of the Journal of Neuroscience, researchers at the ...
Neuroscience
Nov 10, 2011 |
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'If Hamlet give the first or second hit': The development of Burkitt's lymphoma
The human c-myc gene encodes a transcription factor (MYC) involved in the regulation of a vast number of other genes – it has been estimated that the transcription of about one in six genes is somehow under the control ...
Cancer
Nov 08, 2011 |
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How major signaling pathways are wired to our genome gives new insight into disease processes
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each ...
Medical research
Oct 27, 2011 |
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Researchers find coupling of proteins promotes glioblastoma development
Two previously unassociated proteins known to be overly active in a variety of cancers bind together to ignite and sustain malignant brain tumors, a research team led by scientists at The University of Texas MD Anderson Cancer ...
Cancer
Oct 21, 2011 |
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New insight into immune tolerance furthers understanding of autoimmune disease
It is no easy task to preserve the delicate balance that allows us to maintain a strong immune system that can defend us from harmful pathogens, but that is sensitive enough to correctly identify and spare our own cells. ...
Medical research
Sep 15, 2011 |
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Language-related gene responsible for branching of neurons
(Medical Xpress) -- Which genetic mutations enabled the evolution of language? The foxp2 gene plays an important role in language development. Simon E. Fisher at the Max Planck Institute for Psycholinguistics in Nijmegen, ...
Genetics
Sep 01, 2011 |
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Defect in A20 gene expression causes rheumatoid arthritis
Researchers from VIB (Flanders Institute for Biotechnology) and Ghent University have shown that a defective gene can contribute to the onset of rheumatoid arthritis, an often-crippling inflammation of the joints that afflicts ...
Genetics
Aug 16, 2011 |
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Scientists show how fatty diets cause diabetes
Newly diagnosed type 2 diabetics tend to have one thing in common: obesity. Exactly how diet and obesity trigger diabetes has long been the subject of intense scientific research. A new study led by Jamey ...
Medical research
Aug 14, 2011 |
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A novel mechanism that regulates pro-inflammatory cells identified
New research led by Derya Unutmaz, MD associate professor, the Departments of Pathology, Medicine, and Microbiology at NYU School of Medicine and Mark Sundrud, PhD, of Tempero Pharmaceuticals, Inc., has identified a novel ...
Medical research
Aug 10, 2011 |
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Treating obesity via brain glucose sensing
The past two decades have witnessed an epidemic spread of obesity-related diseases in Western countries. Elucidating the biological mechanism that links overnutrition to obesity could prove crucial in reducing obesity levels. ...
Medical research
Jul 26, 2011 |
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