Four decades of research have produced a vast pool of knowledge about regulatory T cells, a subset of our immune cells. Even so, scientists at Purdue University and the National Institutes of Health have identified 14 understudied ...
Aug 2, 2023
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Early on, every stem cell faces a fateful choice. During skin development, for instance, the embryonic epidermis begins as a single layer of epidermal progenitor cells. Their choice is to become a mature epidermal cell or ...
Jul 28, 2023
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New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors—proteins that help turn specific genes on or off by binding to nearby ...
Jul 27, 2023
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A new editorial paper titled "Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma" has been published in Oncotarget.
Jul 19, 2023
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The immune system protects the body from invaders, such as bacteria, viruses, or tumors, with its intricate network of proteins, cells, and organs. Specialized immune cells, called cytotoxic T cells, can develop into short-lived ...
Jun 13, 2023
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Exposure to opioids under chronic pain conditions produces unique gene expression changes in brain regions associated with cognition, emotion, and reward, according to preclinical research conducted at the Icahn School of ...
Jun 9, 2023
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Stem cells from the human stomach can be converted into cells that secrete insulin in response to rising blood sugar levels, offering a promising approach to treating diabetes, according to a preclinical study from researchers ...
May 25, 2023
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Our bodies make blood in a specialized niche—a "nursery" within our bone marrow that nurtures blood stem cells so they can replicate and make different kinds of blood cells. The lab of Leonard Zon, MD, has even shown how ...
May 24, 2023
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A new Nature Immunology study led by University of Pittsburgh and National Institutes of Health researchers sheds light on how a rare type of helper T cell, called Th9, can drive allergic disease, suggesting new precision ...
May 3, 2023
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Mutating cells can prevent the spread of cancer by flipping themselves into a state of reduced activity called senescence. Cancer genes, however, can retaliate by reviving those cells so they can replicate again.
Apr 21, 2023
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