A new editorial paper titled "Predicting the molecular functions of regulatory genetic variants associated with cancer" has been published in Oncotarget.
Nov 20, 2023
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T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known ...
Nov 15, 2023
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Pancreatic cancer is one of the deadliest forms of cancer. This is largely due to the cancer being detected at a late stage. In addition, treatment options for pancreatic cancer are limited.
Oct 5, 2023
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A team of researchers led by Professor Megumu K. Saito have undertaken a massive effort to build an induced pluripotent stem (iPS) cell resource for rare diseases, enabling research and development of novel diagnostic tools ...
Oct 5, 2023
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The microphthalmia-associated transcription factor (MITF) is the master regulator of pigment cell development and, as a lineage survival oncogene, plays a crucial role in the skin cancer melanoma and its resistance to therapy. ...
Oct 2, 2023
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Currently, a lot is known about which genes are responsible for our individual blood groups; however, not much is understood about how and why the levels of the blood group molecules differ between one person and another. ...
Sep 29, 2023
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In recent years, scientists have used gene modification technologies to reprogram immune cells into therapeutics that can attack cancers. But such immunotherapies don't work for all patients or all cancer types, and screening ...
Sep 14, 2023
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There's no question that tumor cells are notoriously skilled masters of immune disguise and, in many ways, real-life versions of what it's like hiding under the fictional invisibility cloak highlighted in the Harry Potter ...
Chronic kidney disease is a condition in which kidney function declines, causing significant health issues in patients. A previous study led by Dr. Motoko Yanagita found that tertiary lymphoid tissues (TLTs), which develop ...
Aug 31, 2023
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Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a ...
Aug 10, 2023
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