Medical research

Elimination of senescent cells improves lung function in mice

Most cells can divide only a limited number of times and eventually undergo permanent cell cycle arrest, a state known as cellular senescence. Cellular senescence is mediated by activation of specific cellular signaling pathways ...

Medical research

New approach to protecting prion protein from altering shape

A team of researchers from Case Western Reserve University School of Medicine have identified a mechanism that can prevent the normal prion protein from changing its molecular shape into the abnormal form responsible for ...

Alzheimer's disease & dementia

Loss of memory in Alzheimer's mice models reversed through gene therapy

Alzheimer's disease is the leading cause of dementia and affects some 400,000 people in Spain alone. However, no effective cure has yet been found. One of the reasons for this is the lack of knowledge about the cellular mechanisms ...

Oncology & Cancer

The novel mechanisms for inflammation and cancer induced by HTLV-1

A research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes inflammation and oncogenesis. The action of the viral gene HTLV-1 bZIP factor (HBZ) ...

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