News tagged with transgenic mouse model
Transgenic mice ready to fight obesity—and more
Scientists at the Nencki Institute of Experimental Biology of the Polish Academy of Sciences in Warsaw investigate mice with a very precisely modified genome. Because it is possible to turn off the Dicer ...
Genetics
Apr 25, 2013 |
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New research method to identify brain tumors could enhance neurosurgery
(Medical Xpress)—The use of a new brain tumor-targeting contrast agent that differentiates between normal and cancer cells in conjunction with a high-powered microscopy system could potentially lead to ...
Cancer
Jan 10, 2013 |
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Study unmasks regulator of healthy life span
A new series of studies in mouse models by Mayo Clinic researchers uncovered that the aging process is characterized by high rates of whole-chromosome losses and gains in various organs, including heart, muscle, kidney and ...
Medical research
Dec 17, 2012 |
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A new development in the relief of spasms related to amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with an occurrence rate in France similar to multiple sclerosis (two to three new cases per year for every 100,000 residents). It has a specific affect on ...
Diseases, Conditions, Syndromes
Nov 06, 2012 |
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Immune cells of the blood might replace dysfunctional brain cells
Blood-circulating immune cells can take over the essential immune surveillance of the brain, this is shown by scientists of the German Center for Neurodegenerative Diseases and the Hertie Institute for Clinical Brain Research ...
Medical research
Oct 22, 2012 |
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Team creates a unique mouse model for the study of aplastic anaemia
Aplastic anaemia is characterised by a reduction in the number of the bone marrow cells that go on to form the different cell types present in blood (essentially red blood cells, white blood cells and platelets). In most ...
Medical research
Aug 29, 2012 |
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A 'Kit' for increasing insulin production
Scientists from Western University in London, Canada and the Children's Health Research Institute, an Institute within the Lawson Health Research Institute, have identified the critical role of a receptor ...
Diabetes
Jul 17, 2012 |
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Researchers develop first mouse model to study important aspect of Alzheimer's
Hirano bodies are almost indescribably tiny objects found in nerve cells of people suffering from conditions such as Alzheimer's, mad cow and Lou Gehrig's diseases. Yet for decades, researchers weren't sure ...
Alzheimer's disease & dementia
Nov 07, 2011 |
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New clues to molecular understanding of autism
The first transgenic mouse model of a rare and severe type of autism called Timothy Syndrome is improving the scientific understanding of autism spectrum disorder in general and may help researchers design more targeted interventions ...
Medical research
Sep 12, 2011 |
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New mouse model for testing cancer drugs
Only one in twenty cancer drugs makes its way from the laboratory to become an approved pharmaceutical product. The majority of new agents are only shown to be unsuitable in the later phases of clinical development which ...
Cancer
Jul 19, 2011 |
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New model for studying germ cell tumors in testes enlists embryonic stem cells
A team of researchers from Spain and Switzerland have developed a new model for studying the development of testicular germ cell tumors by transplanting embryonic stem cells into the seminiferous tubules in mouse models, ...
Cancer
Jul 11, 2011 |
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Case of mistaken identity: Study questions role of A-beta molecules in Alzheimer's disease pathology
Increasingly, researchers are suggesting that amyloid plaques and neurofibrillary tangles may be relatively late manifestations in the course of Alzheimer's disease (AD) pathology. Identifying earlier events ...
Neuroscience
Jun 28, 2011 |
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Novel mouse model provides insight into rare neurodegenerative disease
New research sheds light on common pathogenic mechanisms shared by Huntington's disease (HD) and HD-like disorders. The study, published by Cell Press in the May 12, 2011, issue of the journal Neuron, uses a new transgenic mouse ...
Neuroscience
May 11, 2011 |
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