New discovery could lead to new way to screen drugs for adverse reactions
Adverse drug reactions are a major issue that cause harm, are costly and restrict treatment options for patients and the development of new drugs. A groundbreaking finding by researchers from the La Jolla Institute for Allergy ...
Immunology
May 29, 2012 |
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Gene associated with adolescent idiopathic scoliosis identified
Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian ...
Genetics
May 12, 2013 |
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Discovery pinpoints cause of two types of leukemia, providing insights into new treatment approach
(Medical Xpress)—Patients with two forms of leukemia, who currently have no viable treatment options, may benefit from existing drugs developed for different types of cancer, according to a study conducted by researchers ...
Cancer
May 10, 2013 |
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Mathematical models out-perform doctors in predicting cancer patients' responses to treatment
Mathematical prediction models are better than doctors at predicting the outcomes and responses of lung cancer patients to treatment, according to new research presented today (Saturday) at the 2nd Forum of the European Society ...
Cancer
Apr 20, 2013 |
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Study demonstrates effects of mutant IDH1 and IDH2 inhibitors in primary tumor models
Agios Pharmaceuticals announced today the publication of two articles in the journal Science by Agios scientists and their collaborators demonstrating the effects of the company's small molecule isocitrate dehydrogenase 1 and ...
Cancer
Apr 04, 2013 |
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Asthma drug found highly effective in treating chronic, severe hives and itch
An international team of researchers has found that a once-a-month, high-dose injection of a commonly used asthma drug is highly effective in treating teens and adults chronically afflicted with hives and severe, itchy rash. ...
Immunology
Feb 24, 2013 |
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Gene therapy as a new option for bone defects
(Medical Xpress)—Gene therapy involving modified stem cells obtained from fatty tissue and bone marrow could represent a new option for the treatment of severe orthopaedic injuries to the extremities. This treatment has ...
Medical research
Dec 07, 2012 |
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New drug shrinks brain tumours in melanoma patients
(Medical Xpress)—Australian researchers have given hope to patients with advanced melanoma by showing that a new drug targeting a common mutation in melanoma successfully shrank tumours that had spread to the brain.
Cancer
Oct 08, 2012 |
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Whole-genome scan helps select best treatment for childhood cancer
A whole-genome scan to identify large-scale chromosomal damage can help doctors choose the best treatment option for children with neuroblastoma, one of the most common types of childhood cancer, finds an international collaboration ...
Cancer
Sep 14, 2012 |
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Gene therapy holds promise for reversing congenital hearing loss
A new gene therapy approach can reverse hearing loss caused by a genetic defect in a mouse model of congenital deafness, according to a preclinical study published by Cell Press in the July 26 issue of the journal Neuron. The fi ...
Neuroscience
Jul 25, 2012 |
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Researchers block pathway to cancer cell replication
Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie ...
Cancer
Jul 02, 2012 |
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Researchers review muscular dystrophy therapies
Leading muscular dystrophy researcher Dean Burkin, of the University of Nevada School of Medicine summarizes the impact of a new protein therapeutic, MG53, for the treatment of Duchenne muscular dystrophy ...
Medical research
Jun 22, 2012 |
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Gene clue to drug resistance in African sleeping sickness
(Medical Xpress) -- Researchers have identified a gene that controls susceptibility to drug treatment in Trypanosoma brucei, the parasite responsible for African sleeping sickness.
Diseases, Conditions, Syndromes
Jun 19, 2012 |
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New lab mice cut search for genetic links to disease by more than a decade
With a 95 percent genomic similarity to humans, mice have long been used to learn about the genetic causes of human disease. Once researchers can shine a light on the genetic factors that cause disease in mice, they can start ...
Genetics
Apr 05, 2012 |
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Treatments to reduce anesthesia-induced injury in children show promise in animal studies
Recent clinical studies have shown that general anesthesia can be harmful to infants, presenting a dilemma for both doctors and parents. But new research at Wake Forest Baptist Medical Center may point the way to treatment ...
Neuroscience
Mar 28, 2012 |
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