Disrupting cell signals may lead to new cancer treatments
(Medical Xpress)—Scientists have taken a major step towards developing new treatments for certain cancers by disrupting the internal cellular signals that lead to the uncontrolled growth of cancerous cells.
Cancer
Apr 29, 2013 |
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Virus-like particles provide vital clues about brain tumors
Exosomes are small, virus-like particles that can transport genetic material and signal substances between cells. Researchers at Lund University, Sweden, have made new findings about exosomes released from aggressive brain ...
Medical research
Apr 17, 2013 |
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Biomarker analysis identified women most likely to benefit from T-DM1
For women with metastatic, HER2-positive breast cancer, the amount of HER2 on their tumor might determine how much they benefit from a drug called trastuzumab emtansine (T-DM1), according to data from a subanalysis of the ...
Cancer
Apr 07, 2013 |
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Study reveals that chemotherapy works in an unexpected way
It's generally thought that anticancer chemotherapies work like antibiotics do, by directly killing off what's harmful. But new research published online on April 4 in the Cell Press journal Immunity shows that effective chemot ...
Immunology
Apr 04, 2013 |
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Ophthalmologists urge early diagnosis and treatment of age-related macular degeneration
Age-related macular degeneration (AMD) continues to be the leading cause of visual impairment in the United States for people over age 65, according to a study recently published online in Ophthalmology, the journal of the ...
Ophthalmology
Apr 03, 2013 |
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Common gene variants explain 42% of antidepressant response
Antidepressants are commonly prescribed for the treatment of depression, but many individuals do not experience symptom relief from treatment. The National Institute of Mental Health's STAR*D study, the largest and longest ...
Psychology & Psychiatry
Mar 28, 2013 |
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Major advance in understanding risky but effective multiple sclerosis treatment
A new study by Multiple Sclerosis researchers at three leading Canadian centres addresses why bone marrow transplantation (BMT) has positive results in patients with particularly aggressive forms of MS. The transplantation ...
Neuroscience
Mar 26, 2013 |
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Blood levels of fat cell hormone may predict severity of migraines
In a small, preliminary study of regular migraine sufferers, scientists have found that measuring a fat-derived protein called adiponectin (ADP) before and after migraine treatment can accurately reveal which headache victims ...
Diseases, Conditions, Syndromes
Mar 18, 2013 |
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New effort to identify Parkinson's biomarkers
Last month, the National Institutes of Health announced a new collaborative initiative that aims to accelerate the search for biomarkers—changes in the body that can be used to predict, diagnose or monitor a disease—in ...
Parkinson's & Movement disorders
Mar 05, 2013 |
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Study shows mirabegron effective and well tolerated for overactive bladder
In a new phase III trial mirabegron, a β3-adrenoceptor agonist, given once daily for 12 weeks, reduced the frequency of incontinence episodes and number of daily urinations, and improved urgency and nocturia in adults with ...
Diseases, Conditions, Syndromes
Mar 04, 2013 |
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Study suggests link between untreated depression and response to shingles vaccine
Results from a new study published in Clinical Infectious Diseases suggest a link between untreated depression in older adults and decreased effectiveness of the herpes zoster, or shingles, vaccine. Older adults are known ...
Diseases, Conditions, Syndromes
Feb 14, 2013 |
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Genetically engineered virus kills liver cancer
A genetically-engineered virus tested in 30 terminally-ill liver cancer patients significantly prolonged their lives, killing tumours and inhibiting the growth of new ones, scientists reported on Sunday.
Cancer
Feb 10, 2013 |
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DAI provides potential imaging biomarker to indicate brain tumor response to RT
Diffusion abnormality index (DAI) shows promise as an imaging biomarker to measure brain tumor response to radiation therapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. ...
Cancer
Feb 08, 2013 |
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Transition in cell type parallels treatment response, disease progression in breast cancer
A process that normally occurs in developing embryos – the changing of one basic cell type into another – has also been suspected of playing a role in cancer metastasis. Now a study from Massachusetts General Hospital ...
Cancer
Jan 31, 2013 |
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Singapore scientists discover p53 mutation hinders cancer treatment response
Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant ...
Cancer
Jan 25, 2013 |
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