Singapore scientists discover p53 mutation hinders cancer treatment response
Scientists from the National Cancer Centre Singapore (NCCS) have discovered the workings of the gene that has been hindering treatment response in cancer patients. This discovery was made after 5 years of studying the mutant ...
Cancer
Jan 25, 2013 |
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Personal epigenetic 'signatures' found consistent in prostate cancer patients' metastases
In a genome-wide analysis of 13 metastatic prostate cancers, scientists at the Johns Hopkins Kimmel Cancer Center found consistent epigenetic "signatures" across all metastatic tumors in each patient. The discovery of the ...
Cancer
Jan 23, 2013 |
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Estrogen fights urinary infection in mouse study
(Medical Xpress)—Estrogen levels drop dramatically in menopause, a time when the risk of urinary tract infections increases significantly.
Immunology
Jan 23, 2013 |
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Potential new treatment for gastrointestinal cancers discovered
(Medical Xpress)—Researchers have identified a complex of proteins that promotes the growth of some types of colon and gastric cancers, and shown that medications that block the function of this complex ...
Cancer
Jan 17, 2013 |
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Early treatment for HIV slows damage to immune system and reduces risk of transmission
A 48-week course of antiretroviral medication taken in the early stages of HIV infection slows the damage to the immune system and delays the need for long term treatment, according to research published today in the New En ...
HIV & AIDS
Jan 16, 2013 |
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'Spot' shortages of flu vaccine, tamiflu reported, FDA head says
(HealthDay)—Sporadic shortages of both the flu vaccine and the flu treatment Tamiflu are being reported, as this year's intense flu season continues, according to a top U.S. health official.
Medications
Jan 15, 2013 |
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Sublingual immunotherapy shows promise as treatment for peanut allergy
Peanuts are one of the most common triggers of severe food-induced allergic reactions, which can be fatal, and the prevalence of peanut allergy is increasing. However, there is currently no clinical treatment available for ...
Immunology
Jan 07, 2013 |
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Functional MRI can improve prediction of CBT success
(HealthDay)—Results of functional brain imaging can greatly improve prediction of which patients with social anxiety disorder (SAD) will benefit from cognitive behavioral therapy (CBT), according to a study ...
Psychology & Psychiatry
Jan 04, 2013 |
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Interferon-free therapies for hep C virus look promising
(HealthDay)—For untreated patients with hepatitis C virus (HCV), treatment with an oral nucleotide inhibitor of HCV polymerase, sofosbuvir, plus ribavirin seems effective for genotypes 1, 2, and 3; and ...
Diseases, Conditions, Syndromes
Jan 03, 2013 |
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Data suggest smoking doesn't impact RA treatment response
(HealthDay)—For patients with early rheumatoid arthritis (RA), smoking status does not impact treatment response to early combination therapy or initial methotrexate treatment with step-up therapy, according ...
Arthritis & Rheumatism
Dec 21, 2012 |
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Ability to chart the molecular progress of diabetes brings personalized medicine closer to realization
Researchers in Singapore have succeeded in tracking, for the first time, the molecular changes caused by type 2 diabetes that affect how the body handles glucose production in the liver. In a series of experiments ...
Diabetes
Dec 19, 2012 |
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Immunogenicity strongly impacts response to adalimumab in RA
(HealthDay)—For patients with rheumatoid arthritis (RA), long-term clinical outcomes are good with etanercept and adalimumab; but for adalimumab, treatment response is strongly dependent on the presence ...
Arthritis & Rheumatism
Dec 13, 2012 |
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Genotype predicts treatment related mortality (TRM) in African-American and Asian pediatric AML patients
New research suggests that the presence of a specific genetic marker, known as WT1 SNP rs16754, may be associated with reduced toxicity from chemotherapy in African-American and Asian children with acute myeloid leukemia ...
Cancer
Dec 09, 2012 |
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Boosting immune responses against leukaemia
(Medical Xpress)—In the first of its kind, a translational study undertaken at the Malaghan Institute of Medical Research has revealed that boosting the activity of a rare type of immune cell could be an ...
Cancer
Nov 21, 2012 |
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Factors impacting benefit of exercise in knee OA identified
(HealthDay)—For patients with knee osteoarthritis, self-reported knee instability and fear of physical activity correlate with the likelihood of treatment response following a therapeutic exercise program, ...
Arthritis & Rheumatism
Nov 02, 2012 |
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