Computational tool translates complex data into simplified 2-dimensional images
In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual ...
Medical research
May 19, 2013 |
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Chemical shift MRI helps differentiate renal cell tumors more likely to metastasize
Adding "chemical shift" techniques to MRI can help differentiate clear cell renal cell carcinoma from other types of renal cell cancer, a new study shows. That differentiation can help physicians better determine treatment ...
Cancer
Apr 19, 2013 |
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Association between genetic mutation and risk of death for patients with thyroid cancer
Presence of the genetic mutation BRAF V600E was significantly associated with increased cancer-related death among patients with papillary thyroid cancer (PTC); however, because overall mortality in PTC is low and the association ...
Cancer
Apr 09, 2013 |
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Patients with BRCA1 mutations, but not BRCA2 mutations, had poorer prognosis compared with noncarriers
Patients with breast cancer who had a BRCA1 mutation had significantly worse overall and recurrence-free survival rates compared with patients without BRCA mutations, but no evidence for a difference in survival was found ...
Cancer
Apr 09, 2013 |
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Estrogen plus progestin use linked with increased breast cancer incidence and mortality
Estrogen plus progestin use is linked with increased breast cancer incidence. In addition, prognosis is similar for both users and nonusers of combined hormone therapy, suggesting that mortality from breast cancer may be ...
Cancer
Mar 29, 2013 |
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Biomarker may identify neuroblastomas with sensitivity to BET bromodomain inhibitors
Neuroblastoma, the most common malignant tumor of early childhood, is frequently associated with the presence of MYCN amplification, a genetic biomarker associated with poor prognosis. Researchers have determined that tumors ...
Cancer
Feb 21, 2013 |
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Mohs surgery OK in seniors aged 90 years or older
(HealthDay)—Mohs micrographic surgery (MMS) is safe in seniors aged 90 years or older, according to a study published in the February issue of the Journal of the American Academy of Dermatology.
Surgery
Feb 08, 2013 |
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Black patients with kidney cancer have poorer survival than whites
Among patients with the most common form of kidney cancer, whites consistently have a survival advantage over blacks, regardless of patient and tumor characteristics or surgical treatment. That is the conclusion of a new ...
Cancer
Nov 12, 2012 |
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Ethnic disparities in breast cancer survival remain despite socioeconomic similarities
Disparities in survival after breast cancer persisted across racial/ethnic groups even after researchers adjusted for multiple demographics, such as patients' education and the socioeconomic status of the neighborhood in ...
Cancer
Oct 30, 2012 |
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LPA1 inhibition induces metastatic dormancy in mouse models of breast cancer
A lysophosphatidic acid receptor 1 (LPAR1) inhibitor, known as Debio-0719, suppresses the development of metastases in mice by inducing cancer cell dormancy, according to a study published August 21 in the Journal of the Na ...
Cancer
Aug 21, 2012 |
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Quality of care, other issues may cause worse results in black prostate cancer surgery patients
Black prostate cancer patients may not be getting the same quality of care as white patients, according to a first-of-its-kind study by researchers at Henry Ford Hospital who found racial disparities in the results of surgery ...
Cancer
May 15, 2012 |
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Gender, BMI impact bladder perforation during resection
(HealthDay) -- For patients with bladder tumors, female gender, low body mass index, and tumor characteristics correlate with the risk of bladder perforation during transurethral resection, according to research ...
Diseases, Conditions, Syndromes
Apr 17, 2012 |
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Pancreatic cancer clinical trial results released
The feasibility of selecting treatment based on individual molecular characteristics was demonstrated in a first-of-its kind pancreatic cancer clinical trial reported today by the Translational Genomics Research Institute ...
Cancer
Apr 03, 2012 |
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Single-cell sequencing leads to a new era of cancer research
BGI, the world's largest genomics organization, developed single-cell genome sequencing technology and published two research papers for cancer single-cell sequencing in the research journal Cell. In the papers, which were p ...
Genetics
Mar 02, 2012 |
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The USP15 biological thermostat: A promising novel therapeutic target in cancer
After years studying the molecular bases of glioblastoma - the most common brain tumor and one of the most aggressive of all cancers, the group led by Dr. Joan Seoane , Director of Translational Research at the Vall d'Hebron ...
Cancer
Feb 19, 2012 |
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