Emerging virus in raccoons may provide cancer clues
Rare brain tumors emerging among raccoons in Northern California and Oregon may be linked to a previously unidentified virus discovered by a team of researchers, led by scientists from the University of California, Davis. ...
Diseases, Conditions, Syndromes
Dec 12, 2012 |
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Protein controlling glucose metabolism also a tumor suppressor
A protein known to regulate how cells process glucose also appears to be a tumor suppressor, adding to the potential that therapies directed at cellular metabolism may help suppress tumor growth. In their report in the Dec. ...
Cancer
Dec 06, 2012 |
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A study of fruit fly genes reveals how molecules cooperate to induce tumor formation
Cancer biologists have known for decades that even the most potent cancer-causing genes do not act alone. Yet, identifying which combinations of genetic changes can cause a tumor to form and disease to progress ...
Genetics
Dec 05, 2012 |
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Pathway identified in human lymphoma points way to new blood cancer treatments
A pathway called the "Unfolded Protein Response," or UPR, a cell's way of responding to unfolded and misfolded proteins, helps tumor cells escape programmed cell death during the development of lymphoma.
Cancer
Nov 21, 2012 |
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Study offers clues to cause of kids' brain tumors
(Medical Xpress)—Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.
Genetics
Nov 16, 2012 |
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Inhibition of enzyme NOX4 prevents liver fibrosis
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have led a study published in PLoS One showing that the inhibition of a family member of NADPH oxidase enzyme, NOX4, plays an important role in liver fibros ...
Diseases, Conditions, Syndromes
Nov 05, 2012 |
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Scientists discover gene switch important in cancer
Scientists at Karolinska Institutet in Sweden and the University of Helsinki in Finland have shown that the "switches" that regulate the expression of genes play a major role in the development of cancer. In a study, published ...
Cancer
Nov 01, 2012 |
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Mouse model could help identify viral vectors that may cause tumors
Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect. The study appears in ...
Cancer
Oct 26, 2012 |
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New study finds brain tumors can arise from neurons
(Medical Xpress)—Researchers from the US and Japan have shown that an aggressive type of brain tumor can arise from normal cells in the central nervous system such as neurons. The cells revert to an earlier, ...
Cancer
Oct 19, 2012 |
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Discovery reveals important clues to cancer metastasis
In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority ...
Cancer
Oct 11, 2012 |
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Denosumab reduces burden of giant-cell tumor of the bone
Treatment with denosumab, a drug targeted against a protein that helps promote bone destruction, decreased the number of tumor giant cells in patients with giant-cell tumor of the bone, and increased new bone formation, according ...
Cancer
Sep 21, 2012 |
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Bonanza of genomic sequence data gives researchers valuable new insights into a poorly understood cancer
Stomach cancer doesn't get the same publicity as lung or breast cancer, but it is a health threat to be taken very seriously. "Gastric cancer is the second leading cause of worldwide cancer mortality, with ...
Genetics
Sep 12, 2012 |
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New research sheds light on the molecular mechanisms by which a virus contributes to cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of ...
Cancer
Aug 29, 2012 |
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Common antifungal drug decreases tumor growth and shows promise as cancer therapy
An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this ...
Cancer
Aug 21, 2012 |
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Gene deletion drives more than a quarter of breast cancers
A new study shows that the lack of a certain gene occurs in almost 28 percent of human breast cancers, playing a role in some 60,000 breast cancer cases in the United States and 383,000 worldwide this year.
Genetics
Aug 15, 2012 |
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