The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a limited effect on prostate cancer. EGFR, present on the cell membrane, ...
Dec 22, 2017
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When medication is used to shut off the oxygen supply to tumor cells, the cells adapt their metabolism in the medium term—by switching over to producing energy without oxygen. This observation by biomedical scientists at ...
Apr 28, 2016
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A therapeutic antibody developed by scientists at UCL has been shown to unblock and normalize blood vessels inside cancerous tumors, enabling the more effective delivery of targeted cancer treatments.
Nov 3, 2021
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Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone insulin in their blood can experience increased risks of cancer. Surprisingly, however, Joslin Diabetes Center researchers ...
May 1, 2017
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Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC ...
Nov 13, 2011
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Researchers at the University of Basel took a close look at a signaling pathway present in most organisms and found that it suppresses the formation of specific types of brain tumor. Their results have been published by the ...
Dec 4, 2015
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A protein kinase or enzyme known as PKM2 has proven to control cell division, potentially providing a molecular basis for tumor diagnosis and treatment.
Nov 21, 2014
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Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and is associated with exposure to hepatitis B virus (HBV). Patients carrying the virus have a 100-fold greater risk of developing HCC, ...
Aug 29, 2012
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Researchers at King's College London have identified a new mechanism by which skin damage triggers the formation of tumors, which could have important therapeutic implications for patients suffering with chronic ulcers or ...
Jan 9, 2015
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When our skin is damaged, a whole set of biological processes springs into action to heal the wound. Now, researchers from the VIB-UGent Center for Inflammation Research have shown that one of the molecules involved in this, ...
Nov 26, 2019
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