Pancreatic cancers are deadly and hard to treat, in part because they are so often detected at an advanced stage; overall five-year survival rates are about 11%. Two separate labs at Boston Children's Hospital took out-of-the-box ...
Apr 25, 2023
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Many cancer therapies do not produce the hoped-for results. A common reason for this is that the tumors develop resistance to the medications. This is the case, for example, with alpelisib, a drug that has been approved for ...
Apr 11, 2023
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A key enzyme in sugar metabolism is inactivated particularly easily and efficiently by oxidative stress. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now shown that with this ...
Apr 6, 2023
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Research from Johns Hopkins Kimmel Cancer Center experts revealed a type of RNA, previously considered to be "junk," that may help doctors distinguish and treat a subgroup of patients with medulloblastoma.
Mar 23, 2023
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Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body's anti-cancer immune ...
Feb 14, 2023
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Pancreatic cancer is the third deadliest cancer in the United States, after lung and colorectal, though far less common. It is also among the hardest to effectively treat, with pancreatic cancer stem cells quickly developing ...
Jan 19, 2023
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Because glioblastoma, a highly aggressive and lethal brain cancer, is resistant to conventional therapies, investigators are searching for characteristics of glioblastoma cells that could point to promising drug targets.
Jan 19, 2023
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Cancer is a complex disease and although billions of dollars have been spent on finding safe and effective therapeutics for it, there is still scope for significant development. Researchers have targeted a variety of biological ...
Jan 6, 2023
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The causes of liver cancer are manifold. In addition to metabolic disorders such as those associated with obesity, the main causes in the western world are infections with hepatitis C virus and high alcohol consumption. Although ...
Nov 21, 2022
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Alcohol consumption and hepatitis C viral infection are known risk factors for causing hepatocellular carcinoma, the most common form of liver cancer. Apart from these, obesity-associated nonalcoholic fatty liver disease ...
Oct 17, 2022
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