News tagged with tumor metabolism

Cancer suppressor gene links metabolism with cellular aging

The tumor suppressor protein p53 is an attractive target for drug developers. But this path has so far proven difficult, as most p53 regulatory proteins operate via protein-protein interactions, which make for poor drug targets, ...

Jan 13, 2013
popularity 3.7 / 5 (3) | comments 0 | with audio podcast

New therapeutic approach to fight cancer discovered

Resting cancer cells can be selectively destroyed by inhibiting their energy metabolism. This is the recent discovery by researchers at Charité Universitätsmedizin Berlin and the Max Delbrück Center for ...

Sep 04, 2013
popularity 4.5 / 5 (2) | comments 0 | with audio podcast

Metabolic molecule drives growth of aggressive brain cancer

(Medical Xpress)—A study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) has identified an abnormal ...

Jun 13, 2013
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Tumors disable immune cells by using up sugar

Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned.

Jun 06, 2013
popularity 4.9 / 5 (7) | comments 1 | with audio podcast

Cancer cell metabolism kills

Adenosine-5'-triphosphate (ATP) is the main energy source for all forms of work inside our cells. Scientists from the University of Helsinki, Finland, have found that even a short-term shortage of ATP supply ...

Apr 15, 2013
popularity 5 / 5 (7) | comments 0 | with audio podcast

The metabolic weathervane of cancer

Highly expressed in various cancers and known for its cytoprotective properties, TRAP1 protein has been identified as a potential target for antitumor treatments. As a result of the research conducted by Len Neckers, from ...

Apr 01, 2013
popularity not rated yet | comments 0 | with audio podcast