News tagged with tumor microenvironment
Related topics: cancer cells , breast cancer , cancer , tumor cells
Changing cancer's environment to halt its spread
By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces ...
Cancer
12 hours ago |
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Scientists define a new mechanism leading to tumor hypoxia
An article published recently in Tumor Microenvironment and Therapy - an open access journal by Versita, defines a novel mechanism of tumor hypoxia induced by the longitudinal gradient of residual oxygen along tumor vessel ...
Cancer
May 09, 2013 |
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How some cancers 'poison the soil' to block metastasis
Cancer spread or metastasis can strike unprecedented fear in the minds of cancer patients. The "seed and the soil" hypothesis proposed by Stephen Paget in 1889 is now widely accepted to explain how cancer cells (seeds) are ...
Cancer
Apr 30, 2013 |
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Storming the gates: Study probes how pancreatic cancers metastasize
Researchers at the University of North Carolina at Chapel Hill have discovered that a protein found in the cells surrounding pancreatic cancers play a role in the spread of the disease to other parts of the ...
Cancer
Mar 25, 2013 |
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Key molecule suppresses growth of cancerous liver tumors, study finds
(Medical Xpress)—A molecule already implicated in a number of diverse cellular functions can suppress the growth of tumors in the liver, a Mayo Clinic Cancer Center study has found. Its name is IQGAP1, and when the molecule ...
Cancer
Feb 13, 2013 |
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Tumor cells engineer acidity to drive cell invasion
Researchers at Moffitt Cancer Center and colleagues at Wayne State University School of Medicine investigated the acidity in solid tumors to determine if pH levels play a role in cancer cell invasion in surrounding tissues. ...
Cancer
Jan 25, 2013 |
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Researchers develop novel 3-D culture system for inflammatory breast cancer
Inflammatory breast cancer (IBC) is a very rare and aggressive disease that progresses rapidly and is associated with a very low survival rate. To understand how this type of cancer spreads, it's crucial to characterize the ...
Cancer
Dec 09, 2012 |
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Discovery reveals important clues to cancer metastasis
In recent years investigators have discovered that breast tumors are influenced by more than just the cancer cells within them. A variety of noncancerous cells, which in many cases constitute the majority ...
Cancer
Oct 11, 2012 |
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Stemming the spread of cancer
Okayama University's Masaharu Seno and colleagues have demonstrated in vitro the development of cancer stem cells (CSCs) from a type of normal stem cell exposed to their hypothetical microenvironment of a ...
Cancer
Sep 21, 2012 |
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Taming physical forces that block cancer treatment
A Massachusetts General Hospital research team has identified factors that contribute to solid stress within tumors, suggesting possible ways to alleviate it, and has developed a simple way to measure such pressures.
Cancer
Sep 20, 2012 |
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Tissue around tumor holds key to fighting triple negative breast cancer
A natural substance found in the surrounding tissue of a tumor may be a promising weapon to stop triple negative breast cancer from metastasizing.
Cancer
Sep 19, 2012 |
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Researchers find acidic pH microenvironments in tumors aid tumor cell survival
Researchers at Moffitt Cancer Center and colleagues at the University of South Florida and Wayne State University have discovered that tumor cell survival relies on adaptation to acidic conditions in the tumor microenvironment. ...
Cancer
Sep 06, 2012 |
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Breast density does not influence breast cancer death among breast cancer patients
The risk of dying from breast cancer was not related to high mammographic breast density in breast cancer patients, according to a study published August 20 in the Journal of the National Cancer Institute.
Cancer
Aug 20, 2012 |
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Immune responses can be generated locally within human melanoma skin metastases
In many types of cancer, activated immune cells infiltrate the tumor and influence clinical outcome. It is not always clear where these cells are activated, but results reported in Cancer Research, a journal of the Americ ...
Cancer
Jul 31, 2012 |
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How the fluid between cells affects tumors
There are many factors that affect tumor invasion, the process where a tumor grows beyond the tissue where it first developed. While factors like genetics, tissue type and environmental exposure affect tumor ...
Cancer
Jul 25, 2012 |
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